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7x5h

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'''Unreleased structure'''
 
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The entry 7x5h is ON HOLD
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==Serotonin 5A (5-HT5A) receptor-Gi protein complex==
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<StructureSection load='7x5h' size='340' side='right'caption='[[7x5h]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7x5h]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X5H FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8K3:3-(2-azanylethyl)-1H-indole-5-carboxamide'>8K3</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x5h OCA], [https://pdbe.org/7x5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x5h RCSB], [https://www.ebi.ac.uk/pdbsum/7x5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x5h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Huang S]]
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[[Category: Jiang Y]]
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[[Category: Tan Y]]
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[[Category: Xu HE]]
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[[Category: Xu P]]

Current revision

Serotonin 5A (5-HT5A) receptor-Gi protein complex

PDB ID 7x5h

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