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4cwd

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<StructureSection load='4cwd' size='340' side='right'caption='[[4cwd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4cwd' size='340' side='right'caption='[[4cwd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cwd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CWD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CWD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=449:4-CARBOXY-1,1-DIMETHYLPIPERIDIN-1-IUM'>449</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=449:4-CARBOXY-1,1-DIMETHYLPIPERIDIN-1-IUM'>449</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-butyrobetaine_dioxygenase Gamma-butyrobetaine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.1 1.14.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwd OCA], [https://pdbe.org/4cwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cwd RCSB], [https://www.ebi.ac.uk/pdbsum/4cwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwd OCA], [http://pdbe.org/4cwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cwd RCSB], [http://www.ebi.ac.uk/pdbsum/4cwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BODG_HUMAN BODG_HUMAN]] Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
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[[https://www.uniprot.org/uniprot/BODG_HUMAN BODG_HUMAN]] Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gamma-butyrobetaine dioxygenase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kochan, G]]
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[[Category: Kochan G]]
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[[Category: McDonough, M A]]
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[[Category: McDonough MA]]
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[[Category: Rydzik, A]]
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[[Category: Rydzik A]]
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[[Category: Schofield, C J]]
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[[Category: Schofield CJ]]
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[[Category: 2-og and iron dependent dioxygenase]]
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[[Category: Carnitine biosynthesis]]
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[[Category: Oxidoreductase]]
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Revision as of 07:35, 14 September 2022

CRYSTAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE,2-OXOGLUTARATE IN COMPLEX WITH 449, A NOVEL SUBSTRATE

PDB ID 4cwd

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