1ier

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[[Image:1ier.gif|left|200px]]
[[Image:1ier.gif|left|200px]]
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{{Structure
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|PDB= 1ier |SIZE=350|CAPTION= <scene name='initialview01'>1ier</scene>, resolution 2.26&Aring;
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The line below this paragraph, containing "STRUCTURE_1ier", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=1:Metal-Binding+Site.+Site+1+Is+Exposed+To+The+Exterior+Of+...'>1</scene>, <scene name='pdbsite=2:Metal+Site.+Site+2+Is+Located+Near+The+Inner+Surface+Of+...'>2</scene> and <scene name='pdbsite=3:Metal-Binding+Site+Cd+203+Is+Located+On+A+Two-Fold+Axis+...'>3</scene>
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|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>
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|ACTIVITY=
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|GENE=
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{{STRUCTURE_1ier| PDB=1ier | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ier FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ier OCA], [http://www.ebi.ac.uk/pdbsum/1ier PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ier RCSB]</span>
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'''CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN'''
'''CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN'''
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[[Category: Granier, T.]]
[[Category: Granier, T.]]
[[Category: Precigoux, G.]]
[[Category: Precigoux, G.]]
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[[Category: apoferritin]]
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[[Category: Apoferritin]]
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[[Category: ferritin]]
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[[Category: Ferritin]]
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[[Category: iron storage]]
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[[Category: Iron storage]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:55:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:18:47 2008''
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Revision as of 16:55, 2 May 2008

Template:STRUCTURE 1ier

CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN


Overview

Horse-spleen apoferritin is known to crystallize in three different space groups, cubic F432, tetragonal P42(1)2 and orthorhombic P2(1)2(1)2. A structure comparison of the cubic and tetragonal forms is presented here. Both crystal forms were obtained by the vapor-diffusion technique and data were collected at 2.26 A (cubic crystal) and 2.60 A (tetragonal crystal) resolution. Two main differences were observed between these crystal structures: (i) whereas intermolecular contacts only involve salt-bridge type interactions via cadmium ions in the cubic structure, two types of interactions are observed in the tetragonal crystal (cadmium-ion-mediated salt bridges and hydrogen-bonding interactions) and (ii) cadmium ions bound in the threefold axes of ferritin molecules exhibit lower site-occupation factors in the tetragonal structure than in the cubic one.

About this Structure

1IER is a Single protein structure of sequence from Equus caballus. Full crystallographic information is available from OCA.

Reference

Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin., Granier T, Gallois B, Dautant A, Langlois d'Estaintot B, Precigoux G, Acta Crystallogr D Biol Crystallogr. 1997 Sep 1;53(Pt 5):580-7. PMID:15299889 Page seeded by OCA on Fri May 2 19:55:28 2008

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