This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4dj5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:20, 21 September 2022) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4dj5.png|left|200px]]
 
-
{{STRUCTURE_4dj5| PDB=4dj5 | SCENE= }}
+
==Proteinase K by Langmuir-Blodgett Hanging Drop Method at 1.8A resolution for Unique Water Distribution==
 +
<StructureSection load='4dj5' size='340' side='right'caption='[[4dj5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4dj5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DJ5 FirstGlance]. <br>
 +
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dj5 OCA], [https://pdbe.org/4dj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dj5 RCSB], [https://www.ebi.ac.uk/pdbsum/4dj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dj5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ]] Hydrolyzes keratin at aromatic and hydrophobic residues.
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Langmuir-Blodgett films when used as nanotemplates for crystallization often leads to marked changes in protein stability and structure. Earlier we found that stability of proteins is also correlated with aqueous surroundings in the crystals. Here we study the direct relationships between presence of LB nanotemplates and unique patterns of water molecules surrounding the protein, for four model proteins for which 3D structures are available, and where crystallization conditions for each protein are the same except the presence of LB nanotemplate. Shape of frequency distribution of volumes occupied by water molecules were analyzed. They were found to be different between "classical" samples of different proteins, but surprisingly quite similar for LB samples. Volumes occupied by each water molecule as the function of the distance of the given molecule from the protein surface were studied. Introduction of LB film leads to appearance of water molecules close to protein surface but occupying large volumes. These findings confirm earlier experimental findings on the role of water molecules in determining protein stability and thereby pointing to water as a possible candidate for differences apparent in LB crystal stability against radiation.
-
===Proteinase K by Langmuir-Blodgett Hanging Drop Method at 1.8A resolution for Unique Water Distribution===
+
Unique water distribution of Langmuir-Blodgett versus classical crystals.,Pechkova E, Sivozhelezov V, Belmonte L, Nicolini C J Struct Biol. 2012 Jun 15. PMID:22706161<ref>PMID:22706161</ref>
-
{{ABSTRACT_PUBMED_22706161}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 4dj5" style="background-color:#fffaf0;"></div>
-
==About this Structure==
+
==See Also==
-
[[4dj5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJ5 OCA].
+
*[[Proteinase 3D structures|Proteinase 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:022706161</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Engyodontium album]]
+
</StructureSection>
-
[[Category: Peptidase K]]
+
[[Category: Large Structures]]
-
[[Category: Belmonte, L.]]
+
[[Category: Parengyodontium album]]
-
[[Category: Nicolini, C.]]
+
[[Category: Belmonte L]]
-
[[Category: Pechkova, E.]]
+
[[Category: Nicolini C]]
-
[[Category: Sivozhelezov, V.]]
+
[[Category: Pechkova E]]
-
[[Category: Hydrolase]]
+
[[Category: Sivozhelezov V]]
-
[[Category: Langmuir blodgett]]
+
-
[[Category: Thin film]]
+

Current revision

Proteinase K by Langmuir-Blodgett Hanging Drop Method at 1.8A resolution for Unique Water Distribution

PDB ID 4dj5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4dj5"
Personal tools