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4dlq

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==Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1)==
==Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1)==
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<StructureSection load='4dlq' size='340' side='right' caption='[[4dlq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4dlq' size='340' side='right'caption='[[4dlq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4dlq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DLQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4dlq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DLQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dlo|4dlo]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dlq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlq OCA], [https://pdbe.org/4dlq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dlq RCSB], [https://www.ebi.ac.uk/pdbsum/4dlq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dlq ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Lphn1, Cirl, Cirl1, Cl1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dlq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dlq RCSB], [http://www.ebi.ac.uk/pdbsum/4dlq PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/AGRL1_RAT AGRL1_RAT]] Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Isoform 2: Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4dlq" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Latrophilin|Latrophilin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Arac, D]]
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[[Category: Arac D]]
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[[Category: Bolliger, M F]]
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[[Category: Bolliger MF]]
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[[Category: Boucard, A A]]
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[[Category: Boucard AA]]
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[[Category: Brunger, A T]]
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[[Category: Brunger AT]]
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[[Category: Nguyen, J]]
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[[Category: Nguyen J]]
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[[Category: Soltis, M]]
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[[Category: Soltis M]]
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[[Category: Sudhof, T C]]
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[[Category: Sudhof TC]]
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[[Category: A-latrotoxin]]
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[[Category: Autoproteolysis]]
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[[Category: Extracellular domain]]
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[[Category: Gain domain]]
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[[Category: Hormone binding domain]]
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[[Category: Includes the gps motif]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1)

PDB ID 4dlq

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