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4dxg

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==Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X==
==Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X==
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<StructureSection load='4dxg' size='340' side='right' caption='[[4dxg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4dxg' size='340' side='right'caption='[[4dxg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4dxg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staae Staae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DXG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4dxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DXG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene>, <scene name='pdbligand=PRD_900122:Sialyl-Lewis+X+antigen,+alpha+anomer'>PRD_900122</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dxf|4dxf]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxg OCA], [https://pdbe.org/4dxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dxg RCSB], [https://www.ebi.ac.uk/pdbsum/4dxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxg ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NWMN_0391, ssl4nm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=426430 STAAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxg OCA], [http://pdbe.org/4dxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dxg RCSB], [http://www.ebi.ac.uk/pdbsum/4dxg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxg ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/SSL4_STAAE SSL4_STAAE]] Secreted protein that plays a role in immune innate response inhibition by interfering with host TLR2-mediated pathway.[UniProtKB:Q2G1S8]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Staae]]
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[[Category: Large Structures]]
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[[Category: Baker, E N]]
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[[Category: Staphylococcus aureus subsp. aureus str. Newman]]
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[[Category: Baker, H M]]
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[[Category: Baker EN]]
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[[Category: Fraser, J F]]
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[[Category: Baker HM]]
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[[Category: Hermans, S J]]
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[[Category: Fraser JF]]
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[[Category: Langley, R J]]
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[[Category: Hermans SJ]]
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[[Category: Beta grasp fold]]
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[[Category: Langley RJ]]
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[[Category: Carbohydrate binding]]
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[[Category: Oligonucleotide/oligosaccharide binding fold]]
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[[Category: Sugar binding protein]]
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[[Category: Superantigen fold]]
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Revision as of 08:42, 21 September 2022

Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X

PDB ID 4dxg

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