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4dxg
From Proteopedia
(Difference between revisions)
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==Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X== | ==Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X== | ||
| - | <StructureSection load='4dxg' size='340' side='right' caption='[[4dxg]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='4dxg' size='340' side='right'caption='[[4dxg]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4dxg]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4dxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DXG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene>, <scene name='pdbligand=PRD_900122:Sialyl-Lewis+X+antigen,+alpha+anomer'>PRD_900122</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxg OCA], [https://pdbe.org/4dxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dxg RCSB], [https://www.ebi.ac.uk/pdbsum/4dxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxg ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/SSL4_STAAE SSL4_STAAE]] Secreted protein that plays a role in immune innate response inhibition by interfering with host TLR2-mediated pathway.[UniProtKB:Q2G1S8] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Staphylococcus aureus subsp. aureus str. Newman]] |
| - | [[Category: Baker | + | [[Category: Baker EN]] |
| - | [[Category: | + | [[Category: Baker HM]] |
| - | [[Category: | + | [[Category: Fraser JF]] |
| - | [[Category: | + | [[Category: Hermans SJ]] |
| - | [[Category: | + | [[Category: Langley RJ]] |
| - | + | ||
| - | + | ||
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Revision as of 08:42, 21 September 2022
Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X
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