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4ebl

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==BlaC E166A Faropenem Acyl-Intermediate Complex==
==BlaC E166A Faropenem Acyl-Intermediate Complex==
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<StructureSection load='4ebl' size='340' side='right' caption='[[4ebl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4ebl' size='340' side='right'caption='[[4ebl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ebl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EBL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EBL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ebl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EBL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SFR:(2R)-2-[(1S,2R)-1-CARBOXY-2-HYDROXYPROPYL]-5-[(2R)-TETRAHYDROFURAN-2-YL]-2,3-DIHYDRO-1,3-THIAZOLE-4-CARBOXYLIC+ACID'>SFR</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGF:(2R,5R)-2-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-5-[(2R)-TETRAHYDROFURAN-2-YL]-2,5-DIHYDRO-1,3-THIAZOLE-4-CARBOXYLIC+ACID'>DGF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vff|3vff]], [[3vfh|3vfh]], [[4ebi|4ebi]], [[4ebm|4ebm]], [[4ebn|4ebn]], [[4ebo|4ebo]], [[4ebp|4ebp]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ebl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ebl OCA], [https://pdbe.org/4ebl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ebl RCSB], [https://www.ebi.ac.uk/pdbsum/4ebl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ebl ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ebl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ebl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ebl RCSB], [http://www.ebi.ac.uk/pdbsum/4ebl PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]]
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Mire, J A]]
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[[Category: Mire JA]]
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[[Category: Structural genomic]]
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[[Category: Ambler class a beta-lactamase]]
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[[Category: Esterase]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Serine hydrolase]]
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Current revision

BlaC E166A Faropenem Acyl-Intermediate Complex

PDB ID 4ebl

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