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4eqh

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==Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Trp-AMS==
==Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Trp-AMS==
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<StructureSection load='4eqh' size='340' side='right' caption='[[4eqh]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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<StructureSection load='4eqh' size='340' side='right'caption='[[4eqh]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4eqh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4eqh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EQH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=WSA:5-O-[(L-TRYPTOPHYLAMINO)SULFONYL]ADENOSINE'>WSA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=WSA:5-O-[(L-TRYPTOPHYLAMINO)SULFONYL]ADENOSINE'>WSA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4eqe|4eqe]], [[4eqg|4eqg]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eqh OCA], [https://pdbe.org/4eqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eqh RCSB], [https://www.ebi.ac.uk/pdbsum/4eqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eqh ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eqh OCA], [http://pdbe.org/4eqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eqh RCSB], [http://www.ebi.ac.uk/pdbsum/4eqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eqh ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
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[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4eqh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4eqh" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Fang, P]]
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[[Category: Large Structures]]
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[[Category: Guo, M]]
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[[Category: Fang P]]
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[[Category: Wang, J]]
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[[Category: Guo M]]
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[[Category: Hit domain]]
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[[Category: Wang J]]
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[[Category: Hydrolase]]
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Revision as of 04:09, 7 October 2022

Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Trp-AMS

PDB ID 4eqh

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