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4f8m

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==Crystal structure of Staphylococcal nuclease variant Delta+PHS V23I/I92V at cryogenic temperature==
==Crystal structure of Staphylococcal nuclease variant Delta+PHS V23I/I92V at cryogenic temperature==
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<StructureSection load='4f8m' size='340' side='right' caption='[[4f8m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4f8m' size='340' side='right'caption='[[4f8m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f8m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F8M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f8m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F8M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[4df7|4df7]], [[3va5|3va5]], [[3meh|3meh]], [[3pmf|3pmf]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f8m OCA], [https://pdbe.org/4f8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f8m RCSB], [https://www.ebi.ac.uk/pdbsum/4f8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f8m ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f8m OCA], [http://pdbe.org/4f8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f8m RCSB], [http://www.ebi.ac.uk/pdbsum/4f8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f8m ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
==See Also==
==See Also==
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*[[Staphylococcal nuclease|Staphylococcal nuclease]]
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*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Micrococcal nuclease]]
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[[Category: Large Structures]]
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[[Category: Caro, J A]]
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[[Category: Staphylococcus aureus]]
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[[Category: E., B Garcia-Moreno]]
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[[Category: Caro JA]]
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[[Category: Heroux, A]]
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[[Category: Garcia-Moreno E B]]
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[[Category: Nam, S P]]
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[[Category: Heroux A]]
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[[Category: Schlessman, J L]]
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[[Category: Nam SP]]
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[[Category: Cavity]]
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[[Category: Schlessman JL]]
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[[Category: Hydrolase]]
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[[Category: Hyperstable variant]]
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[[Category: Pdtp]]
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[[Category: Pressure]]
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[[Category: Staphylococcal nuclease]]
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Revision as of 04:41, 7 October 2022

Crystal structure of Staphylococcal nuclease variant Delta+PHS V23I/I92V at cryogenic temperature

PDB ID 4f8m

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