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4fj0

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==Crystal structure of the ternary complex between a fungal 17beta-hydroxysteroid dehydrogenase (Holo form) and 3,7-dihydroxy flavone==
==Crystal structure of the ternary complex between a fungal 17beta-hydroxysteroid dehydrogenase (Holo form) and 3,7-dihydroxy flavone==
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<StructureSection load='4fj0' size='340' side='right' caption='[[4fj0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4fj0' size='340' side='right'caption='[[4fj0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fj0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coclu Coclu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FJ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fj0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Curvularia_lunata Curvularia lunata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FJ0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HHF:3,7-DIHYDROXY-2-PHENYL-4H-CHROMEN-4-ONE'>HHF</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HHF:3,7-DIHYDROXY-2-PHENYL-4H-CHROMEN-4-ONE'>HHF</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3is3|3is3]], [[3qwf|3qwf]], [[3itd|3itd]], [[3qwi|3qwi]], [[3qwh|3qwh]], [[4fiz|4fiz]], [[4fj1|4fj1]], [[4fj2|4fj2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fj0 OCA], [https://pdbe.org/4fj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fj0 RCSB], [https://www.ebi.ac.uk/pdbsum/4fj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fj0 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">17HSDcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5503 COCLU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fj0 OCA], [http://pdbe.org/4fj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fj0 RCSB], [http://www.ebi.ac.uk/pdbsum/4fj0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fj0 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O93874_COCLU O93874_COCLU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4fj0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4fj0" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 17-beta-estradiol 17-dehydrogenase]]
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[[Category: Curvularia lunata]]
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[[Category: Coclu]]
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[[Category: Large Structures]]
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[[Category: Cassetta, A]]
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[[Category: Cassetta A]]
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[[Category: Krastanova, I]]
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[[Category: Krastanova I]]
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[[Category: Lamba, D]]
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[[Category: Lamba D]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Rossmann fold]]
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[[Category: Short chain dehydrogenase/reductase]]
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Revision as of 19:51, 19 October 2022

Crystal structure of the ternary complex between a fungal 17beta-hydroxysteroid dehydrogenase (Holo form) and 3,7-dihydroxy flavone

PDB ID 4fj0

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