This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4fqb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==crystal structure of toxic effector Tse1 in complex with immune protein Tsi1== | ==crystal structure of toxic effector Tse1 in complex with immune protein Tsi1== | ||
| - | <StructureSection load='4fqb' size='340' side='right' caption='[[4fqb]], [[Resolution|resolution]] 2.69Å' scene=''> | + | <StructureSection load='4fqb' size='340' side='right'caption='[[4fqb]], [[Resolution|resolution]] 2.69Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fqb]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4fqb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQB FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqb OCA], [https://pdbe.org/4fqb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqb RCSB], [https://www.ebi.ac.uk/pdbsum/4fqb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqb ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: | + | [[Category: Li L]] |
| - | [[Category: | + | [[Category: Wang T]] |
| - | [[Category: | + | [[Category: Zhang W]] |
| - | + | ||
| - | + | ||
Revision as of 20:05, 19 October 2022
crystal structure of toxic effector Tse1 in complex with immune protein Tsi1
| |||||||||||
