This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4fr8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin==
==Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin==
-
<StructureSection load='4fr8' size='340' side='right' caption='[[4fr8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+
<StructureSection load='4fr8' size='340' side='right'caption='[[4fr8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4fr8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FR8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4fr8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FR8 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TNG:PROPANE-1,2,3-TRIYL+TRINITRATE'>TNG</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TNG:PROPANE-1,2,3-TRIYL+TRINITRATE'>TNG</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zum|1zum]], [[3n80|3n80]], [[3n81|3n81]], [[3n82|3n82]], [[3n83|3n83]], [[2onm|2onm]], [[3inl|3inl]], [[3sz9|3sz9]], [[2onn|2onn]], [[1o05|1o05]], [[2ono|2ono]], [[3inj|3inj]], [[1nzw|1nzw]], [[1nzx|1nzx]], [[1nzz|1nzz]], [[1o00|1o00]], [[1o01|1o01]], [[1o02|1o02]], [[1o04|1o04]], [[2onp|2onp]], [[2vle|2vle]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr8 OCA], [https://pdbe.org/4fr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fr8 RCSB], [https://www.ebi.ac.uk/pdbsum/4fr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fr8 ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALDH2, ALDM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(+)) Aldehyde dehydrogenase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.3 1.2.1.3] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fr8 OCA], [http://pdbe.org/4fr8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fr8 RCSB], [http://www.ebi.ac.uk/pdbsum/4fr8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fr8 ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 20:
==See Also==
==See Also==
-
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
+
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Gruber, K]]
+
[[Category: Large Structures]]
-
[[Category: Lang, B S]]
+
[[Category: Gruber K]]
-
[[Category: Oxidoreductase]]
+
[[Category: Lang BS]]
-
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+
-
[[Category: Rossmann fold]]
+

Revision as of 20:07, 19 October 2022

Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin

PDB ID 4fr8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4fr8"
Personal tools