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7wr7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7wr7 is ON HOLD Authors: Yang, X.L., Ding, Z.Y., Huang, H.J. Description: inhibited-EP Category: Unreleased Structures Category: Yang, X.L ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Inhibited-EP== | |
| - | + | <StructureSection load='7wr7' size='340' side='right'caption='[[7wr7]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7wr7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WR7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GBS:4-GUANIDINOBENZOIC+ACID'>GBS</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wr7 OCA], [https://pdbe.org/7wr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wr7 RCSB], [https://www.ebi.ac.uk/pdbsum/7wr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wr7 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Ding | + | == Disease == |
| - | [[Category: Huang | + | [https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Congenital enteropathy due to enteropeptidase deficiency. The disease is caused by mutations affecting the gene represented in this entry. |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ding ZY]] | ||
| + | [[Category: Huang HJ]] | ||
| + | [[Category: Yang XL]] | ||
Current revision
Structure of Inhibited-EP
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