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4ga1
From Proteopedia
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==Structure of the N-terminal domain of Nup358== | ==Structure of the N-terminal domain of Nup358== | ||
| - | <StructureSection load='4ga1' size='340' side='right' caption='[[4ga1]], [[Resolution|resolution]] 1.15Å' scene=''> | + | <StructureSection load='4ga1' size='340' side='right'caption='[[4ga1]], [[Resolution|resolution]] 1.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ga1]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ga1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pan_troglodytes Pan troglodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GA1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ga1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ga1 OCA], [https://pdbe.org/4ga1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ga1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ga1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ga1 ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RBP2_PANTR RBP2_PANTR] E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB (By similarity). Binds single-stranded RNA (in vitro).<ref>PMID:22959972</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4ga1" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pan troglodytes]] | [[Category: Pan troglodytes]] | ||
| - | [[Category: Hoelz | + | [[Category: Hoelz A]] |
| - | [[Category: Kassube | + | [[Category: Kassube SA]] |
| - | [[Category: Lin | + | [[Category: Lin DH]] |
| - | [[Category: Stuwe | + | [[Category: Stuwe T]] |
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Current revision
Structure of the N-terminal domain of Nup358
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