This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4gdb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:49, 26 October 2022) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==SHV-1 in complex with 4H-pyrazolo[1,5-c][1,3]thiazole containing penem inhibitor==
==SHV-1 in complex with 4H-pyrazolo[1,5-c][1,3]thiazole containing penem inhibitor==
-
<StructureSection load='4gdb' size='340' side='right' caption='[[4gdb]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
+
<StructureSection load='4gdb' size='340' side='right'caption='[[4gdb]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4gdb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GDB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GDB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4gdb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GDB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=17O:(7R)-6-FORMYL-7-(4H-PYRAZOLO[1,5-C][1,3]THIAZOL-2-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC+ACID'>17O</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=17O:(7R)-6-FORMYL-7-(4H-PYRAZOLO[1,5-C][1,3]THIAZOL-2-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC+ACID'>17O</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q2p|1q2p]], [[4gd6|4gd6]], [[4gd8|4gd8]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gdb OCA], [https://pdbe.org/4gdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gdb RCSB], [https://www.ebi.ac.uk/pdbsum/4gdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gdb ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla, shv1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gdb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gdb RCSB], [http://www.ebi.ac.uk/pdbsum/4gdb PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLA1_KLEPN BLA1_KLEPN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 17:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4gdb" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
 
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
-
[[Category: Akker, F van den]]
+
[[Category: Large Structures]]
-
[[Category: Ke, W]]
+
[[Category: Ke W]]
-
[[Category: Class a beta-lactamase]]
+
[[Category: Van den Akker F]]
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+

Current revision

SHV-1 in complex with 4H-pyrazolo[1,5-c][1,3]thiazole containing penem inhibitor

PDB ID 4gdb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gdb"
Personal tools