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4grl

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==Crystal structure of a autoimmune TCR-MHC complex==
==Crystal structure of a autoimmune TCR-MHC complex==
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<StructureSection load='4grl' size='340' side='right' caption='[[4grl]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
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<StructureSection load='4grl' size='340' side='right'caption='[[4grl]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4grl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GRL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4grl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GRL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pl6|3pl6]], [[4may|4may]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4grl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4grl OCA], [https://pdbe.org/4grl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4grl RCSB], [https://www.ebi.ac.uk/pdbsum/4grl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4grl ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alpha chain, HLA-DQ1, HLA-DQA1, MHC CLASS II MOLECULE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), beta chain, HLA-DQ1, HLA-DQB1, MHC CLASS II MOLECULE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), TCR Hy.1B11 alpha chain ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), TCR Hy.1B11 beta chain ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4grl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4grl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4grl RCSB], [http://www.ebi.ac.uk/pdbsum/4grl PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q30066_HUMAN Q30066_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4grl" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Sethi, D K]]
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[[Category: Large Structures]]
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[[Category: Wucherpfennig, K W]]
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[[Category: Sethi DK]]
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[[Category: Autoimmunity]]
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[[Category: Wucherpfennig KW]]
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[[Category: Immune complex]]
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[[Category: Immune system]]
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[[Category: Multiple sclerosis]]
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[[Category: Peptide antigen presentation]]
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Current revision

Crystal structure of a autoimmune TCR-MHC complex

PDB ID 4grl

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