This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


8dwh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:25, 3 November 2022) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8dwh is ON HOLD
+
==CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16==
-
 
+
<StructureSection load='8dwh' size='340' side='right'caption='[[8dwh]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
-
Authors: Youngfeng, L., Cao, C., Fay, J.F., Roth, B.L.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8dwh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DWH FirstGlance]. <br>
-
Description: CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U2U:N-{2-[(1-aminoisoquinolin-6-yl)oxy]-4-methylphenyl}-2-methoxybenzene-1-sulfonamide'>U2U</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dwh OCA], [https://pdbe.org/8dwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dwh RCSB], [https://www.ebi.ac.uk/pdbsum/8dwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dwh ProSAT]</span></td></tr>
-
[[Category: Youngfeng, L]]
+
</table>
-
[[Category: Cao, C]]
+
== Function ==
-
[[Category: Roth, B.L]]
+
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
-
[[Category: Fay, J.F]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Cao C]]
 +
[[Category: Fay JF]]
 +
[[Category: Liu Y]]
 +
[[Category: Roth BL]]

Current revision

CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16

PDB ID 8dwh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8dwh"
Personal tools