This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8a43
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | + | [https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry. | |
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.<ref>PMID:16809778</ref> | |
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Human RNA polymerase I
| |||||||||||
Categories: Homo sapiens | Large Structures | Abascal-Palacios G | Bernecky C | Bleckmann A | Bruckmann A | Daiss JL | Engel C | Fuertges T | Heiss FB | Hoecherl M | Lamour V | Mars JC | Moss T | Panov K | Pilsl M | Ramsay E | Rudack T | Straub K | Tluckova K | Vannini A
