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4h57

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<StructureSection load='4h57' size='340' side='right'caption='[[4h57]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
<StructureSection load='4h57' size='340' side='right'caption='[[4h57]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4h57]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3fwd 3fwd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H57 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4h57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3fwd 3fwd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H57 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PJ:N-[(S)-({[(BENZYLOXY)CARBONYL]AMINO}METHYL)(HYDROXY)PHOSPHORYL]-L-LEUCYL-L-LEUCINE'>0PJ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PJ:N-[(S)-({[(BENZYLOXY)CARBONYL]AMINO}METHYL)(HYDROXY)PHOSPHORYL]-L-LEUCYL-L-LEUCINE'>0PJ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fvp|3fvp]], [[3fv4|3fv4]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h57 OCA], [https://pdbe.org/4h57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h57 RCSB], [https://www.ebi.ac.uk/pdbsum/4h57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h57 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h57 OCA], [http://pdbe.org/4h57 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h57 RCSB], [http://www.ebi.ac.uk/pdbsum/4h57 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h57 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Thermolysin|Thermolysin]]
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thermolysin]]
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[[Category: Biela A]]
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[[Category: Biela, A]]
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[[Category: Englert L]]
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[[Category: Englert, L]]
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[[Category: Heine A]]
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[[Category: Heine, A]]
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[[Category: Klebe G]]
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[[Category: Klebe, G]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metal-binding]]
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[[Category: Metalloprotease]]
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[[Category: Protease]]
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[[Category: Protease phosphonamidate inhibitor]]
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[[Category: Secreted]]
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Revision as of 08:00, 3 November 2022

Thermolysin inhibition

PDB ID 4h57

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