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4ho4

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==Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate==
==Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate==
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<StructureSection load='4ho4' size='340' side='right' caption='[[4ho4]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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<StructureSection load='4ho4' size='340' side='right'caption='[[4ho4]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ho4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aneth Aneth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HO4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ho4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aneurinibacillus_thermoaerophilus Aneurinibacillus thermoaerophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HO4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G1P:ALPHA-D-GLUCOSE-1-PHOSPHATE'>G1P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G1P:ALPHA-D-GLUCOSE-1-PHOSPHATE'>G1P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ho0|4ho0]], [[4ho2|4ho2]], [[4ho3|4ho3]], [[4ho5|4ho5]], [[4ho6|4ho6]], [[4ho8|4ho8]], [[4ho9|4ho9]], [[4hoc|4hoc]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ho4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ho4 OCA], [https://pdbe.org/4ho4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ho4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ho4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ho4 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rmlA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=143495 ANETH])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_thymidylyltransferase Glucose-1-phosphate thymidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.24 2.7.7.24] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ho4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ho4 OCA], [http://pdbe.org/4ho4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ho4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ho4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ho4 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q9AGY4_ANETH Q9AGY4_ANETH]] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706]
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[https://www.uniprot.org/uniprot/Q9AGY4_ANETH Q9AGY4_ANETH] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706]
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==See Also==
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*[[Glucose-1-phosphate thymidylyltransferase 3D structures|Glucose-1-phosphate thymidylyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aneth]]
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[[Category: Aneurinibacillus thermoaerophilus]]
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[[Category: Glucose-1-phosphate thymidylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Chen, T J]]
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[[Category: Chen TJ]]
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[[Category: Chien, W T]]
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[[Category: Chien WT]]
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[[Category: Lin, C C]]
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[[Category: Lin CC]]
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[[Category: Wang, W C]]
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[[Category: Wang WC]]
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[[Category: Nucleotide binding]]
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[[Category: Thymidylyltransferase]]
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[[Category: Transferase]]
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Revision as of 08:29, 3 November 2022

Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate

PDB ID 4ho4

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