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Bromodomain-containing protein 3D structures
From Proteopedia
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| - | *Bromodomain-containing protein 1 | + | *Bromodomain-containing protein 1;Domains – PHD1 zinc finger 208-269; PHD2 zinc finger 317-394; bromodomain 1 555-688; PWWP 925-1049 |
| - | + | **[[2ku3]] – hBRD1 PHD1 zinc finger domain - human - NMR<br /> | |
| - | **[[2ku3]] – hBRD1 PHD1 zinc finger domain | + | **[[2lq6]] – hBRD1 PHD2 zinc finger domain (mutant) - NMR<br /> |
| - | **[[2lq6]] – hBRD1 PHD2 zinc finger domain | + | |
**[[3l43]] – histone H3.3 N-terminal/hBRD1 PHD1 zinc finger domain - NMR<br /> | **[[3l43]] – histone H3.3 N-terminal/hBRD1 PHD1 zinc finger domain - NMR<br /> | ||
| - | **[[3rcw]], [[4z02]] – hBRD1 bromodomain | + | **[[3rcw]], [[4z02]] – hBRD1 bromodomain <br /> |
**[[5pwb]], [[5pwa]], [[5pw9]], [[5pw8]], [[5pw7]], [[5pw6]], [[5pw5]], [[5pw4]], [[5pw3]], [[5pw2]], [[5pw1]], [[5pw0]], [[5pvz]], [[5pvy]], [[5pvx]], [[5pvw]], [[5pvv]], [[5pvu]], [[5pvt]], [[5pvs]], [[5pvr]], [[5pvq]], [[5pvp]], [[5pvo]], [[5pvn]], [[5pvm]], [[5pvl]], [[5pvk]], [[5pvj]], [[5pvi]], [[5pvh]], [[5pvg]], [[5pvf]], [[5pve]], [[5pvd]], [[5pvc]], [[5pvb]], [[5pva]], [[5pv9]], [[5pv8]], [[5pv7]], [[5pv6]], [[5pv5]], [[5pv4]], [[5pv3]], [[5pv2]], [[5pv1]], [[5pv0]], [[5puz]], [[5puy]], [[5pux]], [[5puw]], [[5puv]], [[5puu]], [[5put]], [[5pus]], [[5pur]], [[5puq]], [[5pup]], [[5pun]], [[5pum]], [[5puo]], [[5pul]], [[5puk]], [[5puj]], [[5pui]], [[5puh]], [[5pug]], [[5puf]], [[5pue]], [[5pud]], [[5puc]], [[5pub]], [[5pua]], [[5pu9]], [[5pu8]], [[5pu7]], [[5pu6]], [[5pu5]], [[5pu4]], [[5pu3]], [[5pu2]], [[5pu1]], [[5pu0]], [[5ptz]], [[5pty]], [[5ptx]], [[5ptw]], [[5ptv]], [[5ptu]], [[5pts]], [[5ptt]], [[5ptr]], [[5ptq]], [[5ptp]], [[5pto]], [[5ptn]], [[5ptm]], [[5ptl]], [[5ptk]], [[5ptj]], [[5pth]], [[5ptg]], [[5ptf]], [[5pte]], [[5ptd]], [[5ptc]], [[5ptb]], [[5pta]], [[5pt9]], [[5pt8]], [[5pt7]], [[5pt0]], [[5pt1]], [[5pt2]], [[5pt3]], [[5pt4]], [[5pt5]], [[5pt6]], [[5pnx]], [[5pq0]], [[5pq1]], [[5pq2]], [[5pq3]], [[5pq4]], [[5pq5]], [[5pq6]], [[5pq7]], [[5pq8]], [[5pq9]], [[5pqa]], [[5pqb]], [[5pqc]], [[5pqd]], [[5pqe]], [[5pqf]], [[5pqg]], [[5pqh]], [[5pqi]], [[5pqj]], [[5pqk]], [[5pql]], [[5pqm]], [[5pqn]], [[5pqo]], [[5pqp]], [[5pqq]], [[5pqr]], [[5pqs]], [[5pqt]], [[5pqu]], [[5pqv]], [[5pqw]], [[5pqx]], [[5pqy]], [[5pqz]], [[5pr0]], [[5pr1]], [[5pr2]], [[5pr3]], [[5pr4]], [[5pr5]], [[5pr6]], [[5pr7]], [[5pr8]], [[5pr9]], [[5pra]], [[5prb]], [[5prc]], [[5prd]], [[5pre]], [[5prf]], [[5prg]], [[5prh]], [[5pri]], [[5prj]], [[5prk]], [[5prl]], [[5prm]], [[5prn]], [[5pro]], [[5prp]], [[5prq]], [[5prr]], [[5prs]], [[5prt]], [[5pru]], [[5prv]], [[5prw]], [[5prx]], [[5pry]], [[5prz]], [[5ps0]], [[5ps1]], [[5ps2]], [[5ps3]], [[5ps4]], [[5ps5]], [[5ps6]], [[5ps7]], [[5ps8]], [[5ps9]], [[5psa]], [[5psb]], [[5psc]], [[5psd]], [[5pse]], [[5psf]], [[5psg]], [[5psh]], [[5psi]], [[5psj]], [[5psk]], [[5psl]], [[5psm]], [[5psn]], [[5pso]], [[5psp]], [[5psq]], [[5psr]], [[5pss]], [[5pst]], [[5psu]], [[5psv]], [[5psw]], [[5psx]], [[5psy]], [[5psz]] - hBRD1 residues 555-668 (mutant)<br /> | **[[5pwb]], [[5pwa]], [[5pw9]], [[5pw8]], [[5pw7]], [[5pw6]], [[5pw5]], [[5pw4]], [[5pw3]], [[5pw2]], [[5pw1]], [[5pw0]], [[5pvz]], [[5pvy]], [[5pvx]], [[5pvw]], [[5pvv]], [[5pvu]], [[5pvt]], [[5pvs]], [[5pvr]], [[5pvq]], [[5pvp]], [[5pvo]], [[5pvn]], [[5pvm]], [[5pvl]], [[5pvk]], [[5pvj]], [[5pvi]], [[5pvh]], [[5pvg]], [[5pvf]], [[5pve]], [[5pvd]], [[5pvc]], [[5pvb]], [[5pva]], [[5pv9]], [[5pv8]], [[5pv7]], [[5pv6]], [[5pv5]], [[5pv4]], [[5pv3]], [[5pv2]], [[5pv1]], [[5pv0]], [[5puz]], [[5puy]], [[5pux]], [[5puw]], [[5puv]], [[5puu]], [[5put]], [[5pus]], [[5pur]], [[5puq]], [[5pup]], [[5pun]], [[5pum]], [[5puo]], [[5pul]], [[5puk]], [[5puj]], [[5pui]], [[5puh]], [[5pug]], [[5puf]], [[5pue]], [[5pud]], [[5puc]], [[5pub]], [[5pua]], [[5pu9]], [[5pu8]], [[5pu7]], [[5pu6]], [[5pu5]], [[5pu4]], [[5pu3]], [[5pu2]], [[5pu1]], [[5pu0]], [[5ptz]], [[5pty]], [[5ptx]], [[5ptw]], [[5ptv]], [[5ptu]], [[5pts]], [[5ptt]], [[5ptr]], [[5ptq]], [[5ptp]], [[5pto]], [[5ptn]], [[5ptm]], [[5ptl]], [[5ptk]], [[5ptj]], [[5pth]], [[5ptg]], [[5ptf]], [[5pte]], [[5ptd]], [[5ptc]], [[5ptb]], [[5pta]], [[5pt9]], [[5pt8]], [[5pt7]], [[5pt0]], [[5pt1]], [[5pt2]], [[5pt3]], [[5pt4]], [[5pt5]], [[5pt6]], [[5pnx]], [[5pq0]], [[5pq1]], [[5pq2]], [[5pq3]], [[5pq4]], [[5pq5]], [[5pq6]], [[5pq7]], [[5pq8]], [[5pq9]], [[5pqa]], [[5pqb]], [[5pqc]], [[5pqd]], [[5pqe]], [[5pqf]], [[5pqg]], [[5pqh]], [[5pqi]], [[5pqj]], [[5pqk]], [[5pql]], [[5pqm]], [[5pqn]], [[5pqo]], [[5pqp]], [[5pqq]], [[5pqr]], [[5pqs]], [[5pqt]], [[5pqu]], [[5pqv]], [[5pqw]], [[5pqx]], [[5pqy]], [[5pqz]], [[5pr0]], [[5pr1]], [[5pr2]], [[5pr3]], [[5pr4]], [[5pr5]], [[5pr6]], [[5pr7]], [[5pr8]], [[5pr9]], [[5pra]], [[5prb]], [[5prc]], [[5prd]], [[5pre]], [[5prf]], [[5prg]], [[5prh]], [[5pri]], [[5prj]], [[5prk]], [[5prl]], [[5prm]], [[5prn]], [[5pro]], [[5prp]], [[5prq]], [[5prr]], [[5prs]], [[5prt]], [[5pru]], [[5prv]], [[5prw]], [[5prx]], [[5pry]], [[5prz]], [[5ps0]], [[5ps1]], [[5ps2]], [[5ps3]], [[5ps4]], [[5ps5]], [[5ps6]], [[5ps7]], [[5ps8]], [[5ps9]], [[5psa]], [[5psb]], [[5psc]], [[5psd]], [[5pse]], [[5psf]], [[5psg]], [[5psh]], [[5psi]], [[5psj]], [[5psk]], [[5psl]], [[5psm]], [[5psn]], [[5pso]], [[5psp]], [[5psq]], [[5psr]], [[5pss]], [[5pst]], [[5psu]], [[5psv]], [[5psw]], [[5psx]], [[5psy]], [[5psz]] - hBRD1 residues 555-668 (mutant)<br /> | ||
**[[5n49]] – hBRD1 bromodomain + inhibitor<br /> | **[[5n49]] – hBRD1 bromodomain + inhibitor<br /> | ||
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**[[5amf]] – hBRD1 bromodomain+PHD (mutant) + indazole derivative<br /> | **[[5amf]] – hBRD1 bromodomain+PHD (mutant) + indazole derivative<br /> | ||
**[[5fg6]] – hBRD1 bromodomain+PHD + probe<br /> | **[[5fg6]] – hBRD1 bromodomain+PHD + probe<br /> | ||
| + | **[[3lyi]] – hBRD1 PWWP domain <br /> | ||
| + | **[[7lh9]] – hBRD1 PWWP domain + DNA<br /> | ||
**[[4z02]] – hBRD1 PWWP domain + quinoline derivative<br /> | **[[4z02]] – hBRD1 PWWP domain + quinoline derivative<br /> | ||
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**[[2dvq]], [[2dvr]], [[2dvs]], [[2e3k]] – hBRD2 bromodomain 1 + histone H4 peptide<br /> | **[[2dvq]], [[2dvr]], [[2dvs]], [[2e3k]] – hBRD2 bromodomain 1 + histone H4 peptide<br /> | ||
| + | **[[6u61]], [[6u8h]], [[6ulq]] – hBRD2 bromodomain 1 + peptide <br /> | ||
**[[3oni]] – hBRD2 residues 224-335 + inhibitor<br /> | **[[3oni]] – hBRD2 residues 224-335 + inhibitor<br /> | ||
| - | **[[3aqa]], [[2ydw]], [[2yek]], [[4a9e]], [[4a9f]], [[4a9h]], [[4a9i]], [[4a9j]], [[4a9m]], [[4a9n]], [[4a9o]], [[4alh]], [[4akn]], [[4alg]], [[4uyf]], [[4uyg]], [[4uyh]], [[6db0]], [[6ddi]], [[6k05]], [[6ony]] – hBRD2 N-terminal bromodomain + inhibitor<br /> | + | **[[3aqa]], [[2ydw]], [[2yek]], [[4a9e]], [[4a9f]], [[4a9h]], [[4a9i]], [[4a9j]], [[4a9m]], [[4a9n]], [[4a9o]], [[4alh]], [[4akn]], [[4alg]], [[4uyf]], [[4uyg]], [[4uyh]], [[6db0]], [[6ddi]], [[6jke]], [[6k05]], [[6ony]], [[6tq2]], [[7dpn]], [[7dpo]], [[7env]], [[7lah]], [[7lai]], [[7laj]], [[7lau]], [[7lay]], [[7npy]], [[7mpz]], [[7nq0]], [[7nq1]], [[7nq2]],[[7nq3]], [[7nq5]], [7nq7]], [[7nq8]], [[7nq9]], [7nqi]], [[7nqj]], [[7oe4]], [[7oe5]], [[7oe6]], [[7oe8]], [[7oe9]], [[7oep]], [[7oer]], [[7oes]], [[7oet]], [[7ogy]] – hBRD2 N-terminal bromodomain + inhibitor<br /> |
| - | **[[4mr5]], [[4mr6]], [[4j1p]], [[5ig6]], [[5ek9]], [[5dw1]], [[5xhk]], [[5xhe]], [[5u6v]], [[5n2l]], [[6mo7]], [[6mo8]], [[6mo9]], [[6moa]], [[6dbc]], [[6ddj]], [[6e6j]], [[6fff]], [[6k04]], [[6viy]] – hBRD2 bromodomain 2 + inhibitor<br /> | + | **[[7lak]] – hBRD2 bromodomain 1 + drug<br /> |
| + | **[[4mr5]], [[4mr6]], [[4j1p]], [[5ig6]], [[5ek9]], [[5dw1]], [[5xhk]], [[5xhe]], [[5u6v]], [[5n2l]], [[6mo7]], [[6mo8]], [[6mo9]], [[6moa]], [[6dbc]], [[6ddj]], [[6e6j]], [[6ffe]], [[6fff]], [[6ffg]], [[6k04]], [[6swo]], [[6swp]], [[6viy]], [[6z7f]], [[6z8p]], [[6zb0]], [[6zb1]], [[6zb2]], [[7enz]], [[7eo5]], [[7l6d]], [[7l9g]], [[7l9j]], [[7l9k]], [[7nq5]], [[7nq7]], [[7nq8]], [[7nq9]], [[7nqi]], [[7nqj]], [[7nqi]], [[7q5o]], [[7wln]], [[7wmq]], [[7wmu]], [[7wn5]], [[7wna]], [[7wni]] – hBRD2 bromodomain 2 + inhibitor<br /> | ||
**[[5o3i]], [[5o3h]], [[5o3g]], [[5o3f]], [[5o3e]], [[5o3d]], [[5o3c]], [[5o3b]], [[5o3a]], [[5o39]], [[5o38]], [[6ytm]] – hBRD2 bromodomain 2 (mutant) + inhibitor<br /> | **[[5o3i]], [[5o3h]], [[5o3g]], [[5o3f]], [[5o3e]], [[5o3d]], [[5o3c]], [[5o3b]], [[5o3a]], [[5o39]], [[5o38]], [[6ytm]] – hBRD2 bromodomain 2 (mutant) + inhibitor<br /> | ||
| + | **[[6u71]], [[6ult]], [[7jx7]] – hBRD2 bromodomain 2 + peptide <br /> | ||
**[[5u5s]] – hBRD2 bromodomain 2 + STAT3 peptide - NMR<br /> | **[[5u5s]] – hBRD2 bromodomain 2 + STAT3 peptide - NMR<br /> | ||
**[[5bt5]] – hBRD2 bromodomain 2 + probe<br /> | **[[5bt5]] – hBRD2 bromodomain 2 + probe<br /> | ||
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**[[5dfc]], [[5dfd]] – hBRD2 bromodomain 2 (mutant) + ligand<br /> | **[[5dfc]], [[5dfd]] – hBRD2 bromodomain 2 (mutant) + ligand<br /> | ||
| - | *Bromodomain-containing protein 3 | + | *Bromodomain-containing protein 3; domains – bromodomain 1 24-244; bromodomain 2 307-416; ET 554-640 |
**[[2nxb]] – hBRD3 bromodomain 1<br /> | **[[2nxb]] – hBRD3 bromodomain 1<br /> | ||
**[[2yw5]] – hBRD3 bromodomain 1 - NMR<br /> | **[[2yw5]] – hBRD3 bromodomain 1 - NMR<br /> | ||
| - | **[[3s91]], [[3s92]], [[6qju]] – hBRD3 bromodomain 1 + inhibitor<br /> | + | **[[3s91]], [[3s92]], [[6qju]], [[7laz]] – hBRD3 bromodomain 1 + inhibitor<br /> |
| + | **[[7r8r]] – hBRD3 bromodomain 1 + physachenolide<br /> | ||
| + | **[[6u4a]], [[7rjk]], [[7rjl]], [[7rjm]], [[7rjn]]– hBRD3 bromodomain 1 + peptide<br /> | ||
**[[2oo1]] – hBRD3 bromodomain 2<br /> | **[[2oo1]] – hBRD3 bromodomain 2<br /> | ||
**[[2e7n]] – hBRD3 bromodomain 2 - NMR<br /> | **[[2e7n]] – hBRD3 bromodomain 2 - NMR<br /> | ||
**[[5hfr]] – hBRD3 bromodomain 2 (mutant)<br /> | **[[5hfr]] – hBRD3 bromodomain 2 (mutant)<br /> | ||
| - | **[[5hjc]] – hBRD3 bromodomain 2+ histone H3.1 peptide<br /> | + | **[[5hjc]], [[6ulp]] – hBRD3 bromodomain 2+ histone H3.1 peptide<br /> |
**[[5a7c]] – hBRD3 bromodomain 2 + inhibitor<br /> | **[[5a7c]] – hBRD3 bromodomain 2 + inhibitor<br /> | ||
| - | **[[ | + | **[[7jmy]] – hBRD3 ET domain - NMR<br /> |
| - | **[[6bgg]] – hBRD3 ET domain + | + | **[[6bgg]], [[6bgh]], [[7jq8]], [[7jyn]], [[7jyz]] – hBRD3 ET domain + peptide - NMR<br /> |
**[[2l5e]] – mBRD3 bromodomain 1 + GATA-1 C-terminal – mouse - NMR<br /> | **[[2l5e]] – mBRD3 bromodomain 1 + GATA-1 C-terminal – mouse - NMR<br /> | ||
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**[[2ouo]] – hBRD4 bromodomain 2<br /> | **[[2ouo]] – hBRD4 bromodomain 2<br /> | ||
**[[2i8n]] – hBRD4 bromodomain 2 - NMR<br /> | **[[2i8n]] – hBRD4 bromodomain 2 - NMR<br /> | ||
| - | **[[6bnh]] – hBRD4 ET domain + JMJD6 peptide - NMR<br /> | ||
**[[3jvj]] – mBRD4 bromodomain 1<br /> | **[[3jvj]] – mBRD4 bromodomain 1<br /> | ||
**[[2dww]], [[3jvl]], [[3jvm]] – mBRD4 bromodomain 2<br /> | **[[2dww]], [[3jvl]], [[3jvm]] – mBRD4 bromodomain 2<br /> | ||
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*Bromodomain-containing protein 4 bromodomain 1 residues 44-168 complex | *Bromodomain-containing protein 4 bromodomain 1 residues 44-168 complex | ||
| - | + | **[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]], [[5y1y]], [[5wuu]], [[5vom]], [[5v67]], [[5uvw]], [[5ula]], [[5ti7]], [[5n2m]], [[5mli]], [[5mkz]], [[5m3a]], [[5m39]], [[5lrq]], [[5kj0]], [[5kdh]], [[5h21]], [[5f5z]], [[6q3y]], [[6q3z]], [[6mau]], [[6hdq]], [[6fnx]], [[6fo5]], [[6fsy]], [[6ft3]], [[6ft4]], [[6e4a]], [[6dmj]], [[6dml]], [[6djc]], [[6czu]], [[6czv]], [[6ckr]], [[6cks]], [[6cis]], [[6ciy]], [[6cj1]], [[6cj2]], [[6cd4]], [[6cd5]], [[6afr]], [[5z1r]], [[5z1s]], [[5z1t]], [[5z5t]], [[5z5u]], [[5z5v]], [[5z8g]], [[5z8r]], [[5z8z]], [[5z90]], [[5z9k]], [[5yqx]], [[5y93]], [[5y94]], [[5y8c]], [[5y8w]], [[5y8w]], [[5y8y]], [[5y8z]], [[5xhy]], [[5xi2]], [[5xi3]], [[5xi4]], [[5wma]], [[5wa5]], [[5w55]], [[5vzs]], [[5vbp]], [[5vbo]], [[5ovb]], [[5o97]], [[6ajv]], [[6ajw]], [[6ajx]], [[6ajy]], [[6dl2]], [[6i7x]], [[67iy]], [[6in1]], [[6in2]], [[6ji3]], [[6ji4]], [[6ji5]], [[6jj3]], [[6jj5]], [[6jj6]], [[6jjb]], [[6kec]], [[6ked]], [[6kee]], [[6kef]], [[6keg]], [[6keh]], [[6kei]], [[6kej]], [[6kek]], [[6lg4]], [[6lg5]], [[6lg6]], [[6lg7]], [[6lg8]], [[6lg9]], [[6lih]], [[6lim]], [[6mh1]], [[6mh7]], [[6p05]], [[6prt]], [[6ps9]], [[6psb]], [[6rwj]], [[6s25]], [[6se4]], [[6swn]], [[6swq]], [[6tpx]], [[6tpy]], [[6tpz]], [[6tq1]], [[6u0d]], [[6uvj]], [[6uvm]], [[6uwu]], [[6uwx]], [[6v0u]], [[6v1k]], [[6v1l]], [[6v1u]], [[6viw]], [[6vix]], [[6viz]], [[6vub]], [[6vuc]], [[6vuf]], [[6vuj]], [[6wgx]], [[6ww8]], [[6x7b]], [[6x7c]], [[6x7d]], [[6yin]], [[6yqn]], [[6yqo]], [[6yqp]], [[6z7g]], [[6z7l]], [[6z7m]], [[6zed]], [[6zel]], [[6zf9]], [[7c2z]], [[7a9u]], [[7ajn]], [[7axr]], [[7b1t]], [[7c6p]], [[7dhs]], [[7ehw]], [[7ehy]], [[7eig]], [[7eik]], [[7eil]], [[7fh2]], [[7k6g]], [[7k6h]], [[7khl]], [[7kkw]], [[7jkw]], [[7jkx]], [[7jky]], [[7l9m]], [[7la9]], [[7lh8]], [[7m16]], [[7mce]], [[7mcf]], [[7mlq]], [[7mlr]], [[7mls]], [[7mr5]], [[7mr6]], [[7mr7]], [[7mr8]], [[7mr9]], [[7mra]], [[7mrb]], [[7rn2]], [[7o18]], [[7oeo]], [[7p6v]], [[7p6w]], [[7p6y]], [[7q3f]], [[7r9c]], [[7rek]], [[7rel]], [[7rem]], [[7rui]], [[7rxr]], [[7rxs]], [[7rxt]], [[7t3f]], [[7uty]], [[7uzn]], [[7v1u]], [[7v2j]], [[7w3d]], [[7wjs]], [[7wky]], [[7wl4]], [[7wwz]], [[8ead]] – hBRD4 bromodomain 1 + inhibitor<br /> | |
| - | + | **[[5ti6]], [[5ti5]], [[5ti4]], [[5ti3]], [[5ti2]], [[5you]], [[5yov]], [[5wmd]], [[5wmg]], [[6g0d]], [[6g0e]], [[6g0f]], [[6g0g]], [[6g0h]], [[6hov]] – hBRD4 bromodomain 1 (mutant) + inhibitor<br /> | |
| - | + | ||
| - | **[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]], [[5y1y]], [[5wuu]], [[5vom]], [[5v67]], [[5uvw]], [[5ula]], [[5ti7]], [[5n2m]], [[5mli]], [[5mkz]], [[5m3a]], [[5m39]], [[5lrq]], [[5kj0]], [[5kdh]], [[5h21]], [[5f5z]], [[6q3y]], [[6q3z]], [[6mau]], [[6hdq]], [[6fnx]], [[6fo5]], [[6fsy]], [[6ft3]], [[6ft4]], [[6e4a]], [[6dmj]], [[6dml]], [[6djc]], [[6czu]], [[6czv]], [[6ckr]], [[6cks]], [[6cis]], [[6ciy]], [[6cj1]], [[6cj2]], [[6cd4]], [[6cd5]], [[6afr]], [[5z1r]], [[5z1s]], [[5z1t]], [[5z5t]], [[5z5u]], [[5z5v]], [[5z8g]], [[5z8r]], [[5z8z]], [[5z90]], [[5z9k]], [[5yqx]], [[5y93]], [[5y94]], [[5y8c]], [[5y8w]], [[5y8w]], [[5y8y]], [[5y8z]], [[5xhy]], [[5xi2]], [[5xi3]], [[5xi4]], [[5wma]], [[5wa5]], [[5w55]], [[5vzs]], [[5vbp]], [[5vbo]], [[5ovb]], [[5o97]], [[6ajv]], [[6ajw]], [[6ajx]], [[6ajy]], [[6dl2]], [[6i7x]], [[67iy]], [[6in1]], [[6in2]], [[6ji3]], [[6ji4]], [[6ji5]], [[6jj3]], [[6jj5]], [[6jj6]], [[6jjb]], [[6mh1]], [[6mh7]], [[6p05]], [[6prt]], [[6ps9]], [[6psb]], [[6s25]], [[6se4]], [[6uvj]], [[6uvm]], [[6uwu]], [[6uwx]], [[6v0u]], [[6v1k]], [[6v1l]], [[6v1u]], [[6viw]], [[6vix]], [[6vub]], [[6vuc]], [[6vuf]], [[6vuj]], [[6yin]], [[6yqn]], [[6yqo]], [[6yqp]] – hBRD4 bromodomain 1 + inhibitor<br /> | + | |
| - | **[[6g0d]], [[6g0e]], [[6g0f]], [[6g0g]], [[6g0h]], [[6hov]] – hBRD4 bromodomain 1 (mutant) + inhibitor<br /> | + | |
**[[5z9c]] – hBRD4 bromodomain 1 + inhibitor - NMR<br /> | **[[5z9c]] – hBRD4 bromodomain 1 + inhibitor - NMR<br /> | ||
| - | **[[5ti6]], [[5ti5]], [[5ti4]], [[5ti3]], [[5ti2]], [[5you]], [[5yov]], [[5wmd]], [[5wmg]] – hBRD4 bromodomain 1 (mutant) + inhibitor <br /> | ||
**[[4lys]], [[4lzr]], [[6ajz]] – hBRD4 bromodomain 1 + colchiceine<br /> | **[[4lys]], [[4lzr]], [[6ajz]] – hBRD4 bromodomain 1 + colchiceine<br /> | ||
**[[4qb3]] – hBRD4 bromodomain 1 + olinone<br /> | **[[4qb3]] – hBRD4 bromodomain 1 + olinone<br /> | ||
| Line 82: | Line 83: | ||
**[[5igk]] – hBRD4 bromodomain 1 + bromosporine<br /> | **[[5igk]] – hBRD4 bromodomain 1 + bromosporine<br /> | ||
**[[5hcl]] – hBRD4 bromodomain 1 + drug<br /> | **[[5hcl]] – hBRD4 bromodomain 1 + drug<br /> | ||
| + | **[[6u6k]], [[6u72]], [[6u74]], [[6u8m]], [[6uls]], [[6ulv]] – hBRD4 bromodomain 1 + cyclic peptide<br /> | ||
**[[6bn7]], [[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] – hBRD4 bromodomain 1 (mutant) + DNA damage-binding protein + cereblon<br /> | **[[6bn7]], [[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] – hBRD4 bromodomain 1 (mutant) + DNA damage-binding protein + cereblon<br /> | ||
| - | **[[ | + | **[[7khh]], [[7znt]] – hBRD4 bromodomain 1 + elongin-B + elongin-C + PVHL peptide + inhibitor<br /> |
**[[3uvw]], [[3uvy]], [[3uvx]], [[3uw9]] – hBRD4 bromodomain 1 + histone H4 peptide<br /> | **[[3uvw]], [[3uvy]], [[3uvx]], [[3uw9]] – hBRD4 bromodomain 1 + histone H4 peptide<br /> | ||
| + | **[[7tuq]], [[7tv0]] – hBRD4 bromodomain 1 + SARS peptide<br /> | ||
| + | **[[4kv1]], [[5nng]], [[5nnf]], [[5nne]], [[5nng]], [[5nnf]], [[5nne]], [[7rjo]], [[7rjp]], [[7rjq]], [[7rjr]] – hBRD4 bromodomain 1 + peptide<br /> | ||
| + | **[[6bnh]] – hBRD4 ET domain + JMJD6 peptide - NMR<br /> | ||
**[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br /> | **[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br /> | ||
**[[3jvk]], [[3muk]], [[3mul]], [[5nnd]], [[5nnc]] – mBRD4 bromodomain 1 + histone H3.3 peptide<br /> | **[[3jvk]], [[3muk]], [[3mul]], [[5nnd]], [[5nnc]] – mBRD4 bromodomain 1 + histone H3.3 peptide<br /> | ||
| Line 90: | Line 95: | ||
*Bromodomain-containing protein 4 bromodomain 2 residues 344-455 complex | *Bromodomain-containing protein 4 bromodomain 2 residues 344-455 complex | ||
| - | **[[2yem]], [[4z93]], [[5u2c]], [[5jwm]], [[5uvz]], [[5uvy]], [[5uvx]], [[5uvv]], [[5uvu]], [[5uvt]], [[5uvs]], [[5uoo]], [[5uf0]], [[5uez]], [[5uey]], [[5uex]], [[5uew]], [[5uev]], [[5ueu]], [[5uet]], [[5ues]], [[5uer]], [[5ueq]], [[5uep]], [[5ueo]], [[6ffd]], [[6ffe]], [[6ffg]], [[6c7q]], [[6c7r]], [[6duv]], [[6i80]], [[6i81]], [[ | + | **[[2yem]], [[4z93]], [[5u2c]], [[5jwm]], [[5uvz]], [[5uvy]], [[5uvx]], [[5uvv]], [[5uvu]], [[5uvt]], [[5uvs]], [[5uoo]], [[5uf0]], [[5uez]], [[5uey]], [[5uex]], [[5uew]], [[5uev]], [[5ueu]], [[5uet]], [[5ues]], [[5uer]], [[5ueq]], [[5uep]], [[5ueo]], [[6ffd]], [[6ffe]], [[6ffg]], [[6c7q]], [[6c7r]], [[6duv]], [[6i80]], [[6i81]], [[6zb3]], [[7c6p]], [[7jkz]], [[7ko0]], [[7ruh]] – hBRD4 bromodomain 2 + inhibitor<br /> |
| + | **[[7aqt]] – hBRD4 bromodomain 2 + inhibitor - NMR<br /> | ||
**[[2lsp]] – hBRD4 bromodomain 2 + Nf-Kb peptide<br /> | **[[2lsp]] – hBRD4 bromodomain 2 + Nf-Kb peptide<br /> | ||
**[[4kv4]] – hBRD4 bromodomain 2 + Rel peptide<br /> | **[[4kv4]] – hBRD4 bromodomain 2 + Rel peptide<br /> | ||
**[[2mjv]] – hBRD4 bromodomain 2 + Twist peptide<br /> | **[[2mjv]] – hBRD4 bromodomain 2 + Twist peptide<br /> | ||
**[[6mnl]] – hBRD4 bromodomain 2 + foxo3a peptide<br /> | **[[6mnl]] – hBRD4 bromodomain 2 + foxo3a peptide<br /> | ||
| + | **[[6ko2]] – hBRD4 bromodomain 2 + histone peptide<br /> | ||
| + | **[[6u6l]], [[6u8g]], [[6u8i]] – hBRD4 bromodomain 2 + cyclic peptide<br />]], [[6y7h]], [[6y7j]], [[6y7k]], [[6y7i]], [[6y7l]], [[6yqr]], [[6yqs]], [6yqw]], [[6yqz]] | ||
**[[5t35]], [[6sis]] – hBRD4 bromodomain 2 + elongin-B + elongin-C + PVHL peptide<br /> | **[[5t35]], [[6sis]] – hBRD4 bromodomain 2 + elongin-B + elongin-C + PVHL peptide<br /> | ||
| Line 109: | Line 117: | ||
**[[5igm]] – hBRD9 bromodomain + bromosporine <br /> | **[[5igm]] – hBRD9 bromodomain + bromosporine <br /> | ||
**[[6v0x]] – hBRD9 bromodomain + sunitinib <br /> | **[[6v0x]] – hBRD9 bromodomain + sunitinib <br /> | ||
| - | **[[4nqn]], [[4xy8]], [[4z6h]], [[4z6i]], [[5e9v]], [[5f2p]], [[5f25]], [[5f1l]], [[5f1h]], [[5eu1]], [[5mky]], [[6hm0]], [[6bqa]], [[6v0s]], [[6v14]], [[6v1b]] – hBRD9 bromodomain + inhibitor<br /> | + | **[[4nqn]], [[4xy8]], [[4z6h]], [[4z6i]], [[5e9v]], [[5f2p]], [[5f25]], [[5f1l]], [[5f1h]], [[5eu1]], [[5mky]], [[6hm0]], [[6bqa]], [[6v0s]], [[6v14]], [[6v1b]], [[6y7h]], [[6y7j]], [[6y7k]], [[6y7i]], [[6y7l]], [[6yqr]], [[6yqs]], [6yqw]], [[6yqz]], [[8a71]] – hBRD9 bromodomain + inhibitor<br /> |
**[[4yy4]] – hBRD9 bromodomain + DMSO<br /> | **[[4yy4]] – hBRD9 bromodomain + DMSO<br /> | ||
**[[4yy6]], [[4yyd]], [[4yyg]], [[4yyh]], [[4yyj]], [[4yyk]], [[4yyi]] – hBRD9 bromodomain + histone H4 peptide<br /> | **[[4yy6]], [[4yyd]], [[4yyg]], [[4yyh]], [[4yyj]], [[4yyk]], [[4yyi]] – hBRD9 bromodomain + histone H4 peptide<br /> | ||
Current revision
3D Structures of bromodomain-containing protein
Updated on 06-November-2022
