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3zpk

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==Atomic-resolution structure of a quadruplet cross-beta amyloid fibril==
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<StructureSection load='3zpk' size='340' side='right' caption='[[3zpk]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
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==Atomic-resolution structure of a quadruplet cross-beta amyloid fibril.==
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<SX load='3zpk' size='340' side='right' viewer='molstar' caption='[[3zpk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zpk]] is a 16 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zpk]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The September 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloids'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_9 10.2210/rcsb_pdb/mom_2015_9]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2m5k|2m5k]], [[2m5m|2m5m]], [[2m5n|2m5n]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpk OCA], [https://pdbe.org/3zpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpk RCSB], [https://www.ebi.ac.uk/pdbsum/3zpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpk ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpk RCSB], [http://www.ebi.ac.uk/pdbsum/3zpk PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.,Fitzpatrick AW, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller SA, MacPhee CE, Waudby CA, Mott HR, De Simone A, Knowles TP, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5468-73. doi:, 10.1073/pnas.1219476110. Epub 2013 Mar 19. PMID:23513222<ref>PMID:23513222</ref>
Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.,Fitzpatrick AW, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller SA, MacPhee CE, Waudby CA, Mott HR, De Simone A, Knowles TP, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5468-73. doi:, 10.1073/pnas.1219476110. Epub 2013 Mar 19. PMID:23513222<ref>PMID:23513222</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3zpk" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Bajaj, V S.]]
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[[Category: Amyloids]]
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[[Category: Bayro, M J.]]
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[[Category: Large Structures]]
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[[Category: Caporini, M A.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Clare, D K.]]
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[[Category: Rattus norvegicus]]
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[[Category: Debelouchina, G T.]]
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[[Category: Bajaj VS]]
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[[Category: Dobson, C M.]]
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[[Category: Bayro MJ]]
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[[Category: Fitzpatrick, A w.P.]]
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[[Category: Caporini MA]]
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[[Category: Griffin, R G.]]
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[[Category: Clare DK]]
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[[Category: Jaroniec, C P.]]
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[[Category: Debelouchina GT]]
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[[Category: Knowles, T P.J.]]
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[[Category: Dobson CM]]
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[[Category: Ladizhansky, V.]]
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[[Category: Fitzpatrick AWP]]
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[[Category: MacPhee, C E.]]
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[[Category: Griffin RG]]
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[[Category: Mott, H R.]]
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[[Category: Jaroniec CP]]
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[[Category: Muller, S A.]]
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[[Category: Knowles TPJ]]
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[[Category: Orlova, E V.]]
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[[Category: Ladizhansky V]]
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[[Category: Saibil, H R.]]
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[[Category: MacPhee CE]]
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[[Category: Simone, A de.]]
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[[Category: Mott HR]]
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[[Category: Vendruscolo, M.]]
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[[Category: Muller SA]]
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[[Category: Wang, L.]]
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[[Category: Orlova EV]]
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[[Category: Waudby, C A.]]
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[[Category: Saibil HR]]
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[[Category: Cross-beta structure]]
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[[Category: Vendruscolo M]]
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[[Category: Protein fibril]]
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[[Category: Wang L]]
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[[Category: Waudby CA]]
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[[Category: De Simone A]]

Current revision

Atomic-resolution structure of a quadruplet cross-beta amyloid fibril.

3zpk

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