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4i3u

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==Structure of phosphonoacetaldehyde dehydrogenase in complex with phosphonoacetaldehyde==
==Structure of phosphonoacetaldehyde dehydrogenase in complex with phosphonoacetaldehyde==
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<StructureSection load='4i3u' size='340' side='right' caption='[[4i3u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4i3u' size='340' side='right'caption='[[4i3u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4i3u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ensifer_meliloti Ensifer meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I3U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4i3u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I3U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POA:PHOSPHONOACETALDEHYDE'>POA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POA:PHOSPHONOACETALDEHYDE'>POA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i3t|4i3t]], [[4i3v|4i3v]], [[4i3w|4i3w]], [[4i3x|4i3x]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3u OCA], [https://pdbe.org/4i3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i3u RCSB], [https://www.ebi.ac.uk/pdbsum/4i3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3u ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">phnY, RB0979, SM_b21539 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266834 Ensifer meliloti])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(+)) Aldehyde dehydrogenase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.3 1.2.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i3u RCSB], [http://www.ebi.ac.uk/pdbsum/4i3u PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHNY_RHIME PHNY_RHIME] Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA). Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.<ref>PMID:24361046</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4i3u" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
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*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ensifer meliloti]]
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[[Category: Large Structures]]
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[[Category: Agarwal, V]]
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[[Category: Sinorhizobium meliloti 1021]]
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[[Category: Nair, S K]]
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[[Category: Agarwal V]]
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[[Category: Aldehyde dehydrogenase]]
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[[Category: Nair SK]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphonate catabolism]]
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Current revision

Structure of phosphonoacetaldehyde dehydrogenase in complex with phosphonoacetaldehyde

PDB ID 4i3u

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