This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Cathepsin 3D structures
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 9: | Line 9: | ||
**[[4cia]], [[4cib]] - hCTSB + inhibitor<br /> | **[[4cia]], [[4cib]] - hCTSB + inhibitor<br /> | ||
| - | * Procathepsin-B | + | *Cathepsin-A |
| + | |||
| + | **[[7kdv]] - hCTSB in Lysosomal Multienzyme Complex – Cryo EM<br /> | ||
| + | |||
| + | * Procathepsin-B or cysteine peptidase | ||
**[[1pbh]], [[2pbh]], [[3pbh]] – hPCTSB <br /> | **[[1pbh]], [[2pbh]], [[3pbh]] – hPCTSB <br /> | ||
**[[1mir]] - rPCTSB (mutant) - rat<br /> | **[[1mir]] - rPCTSB (mutant) - rat<br /> | ||
**[[4n4z]], [[4hwy]] - TbCTSB – ''Trypanosoma brucei''<br /> | **[[4n4z]], [[4hwy]] - TbCTSB – ''Trypanosoma brucei''<br /> | ||
| - | **[[5fpw]] – TbCTSB (mutant)<br /> | + | **[[5fpw]], [[7e3e]], [[7e3f]], [[7e3g]] – TbCTSB (mutant)<br /> |
* Cathepsin-B mature | * Cathepsin-B mature | ||
| Line 39: | Line 43: | ||
**[[1k3b]] – hMCTSC <br /> | **[[1k3b]] – hMCTSC <br /> | ||
**[[2djf]], [[2djg]], [[4oel]], [[4oem]] – hMCTSC + dipeptide<br /> | **[[2djf]], [[2djg]], [[4oel]], [[4oem]] – hMCTSC + dipeptide<br /> | ||
| - | **[[3pdf]], [[4cdc]], [[4cdd]], [[4cde]], [[4cdf]] – hMCTSC + inhibitor<br /> | + | **[[3pdf]], [[4cdc]], [[4cdd]], [[4cde]], [[4cdf]], [[6ic5]], [[6ic6]], [[6ic7]], [[6rn6]], [[6rn7]], [[6rn9]], [[6rni]] – hMCTSC + inhibitor<br /> |
**[[1jqp]] – rMCTSC <br /> | **[[1jqp]] – rMCTSC <br /> | ||
| Line 81: | Line 85: | ||
* Cathepsin-K mature | * Cathepsin-K mature | ||
| - | **[[4n79]], [[5tun]], [[4yva]] – hMCTSK<br /> | + | **[[4n79]], [[5tun]], [[4yva]], [[7pck]] – hMCTSK<br /> |
**[[5jh3]], [[5z5o]] – hMCTSK (mutant) <br /> | **[[5jh3]], [[5z5o]] – hMCTSK (mutant) <br /> | ||
**[[3o1g]], [[3n3g]], [[2r6n]], [[1bgo]], [[3kwz]], [[3kx1]], [[3o0u]] – hMCTSK+ pyrimidine inhibitor<br /> | **[[3o1g]], [[3n3g]], [[2r6n]], [[1bgo]], [[3kwz]], [[3kx1]], [[3o0u]] – hMCTSK+ pyrimidine inhibitor<br /> | ||
| Line 101: | Line 105: | ||
**[[1au2]] - hMCTSK+ propanone inhibitor<br /> | **[[1au2]] - hMCTSK+ propanone inhibitor<br /> | ||
**[[1atk]] – hMCTSK+guanidine inhibitor<br /> | **[[1atk]] – hMCTSK+guanidine inhibitor<br /> | ||
| - | **[[1vsn]], [[5j94]], [[4x6h]], [[4x6i]], [[6qbs]], [[6hgy]], [[6qlx]], [[6qm0]] - hMCTSK+ inhibitor<br /> | + | **[[1vsn]], [[5j94]], [[4x6h]], [[4x6i]], [[6qbs]], [[6hgy]], [[6pxf]], [[6qlx]], [[6qm0]], [[7nxl]], [[7qbm]], [[7qbn]], [[7qbo]] - hMCTSK+ inhibitor<br /> |
**[[6ash]] – hMCTSK (mutant) + inhibitor<br /> | **[[6ash]] – hMCTSK (mutant) + inhibitor<br /> | ||
**[[2ato]] – hMCTSK+myocrisin<br /> | **[[2ato]] – hMCTSK+myocrisin<br /> | ||
| Line 168: | Line 172: | ||
**[[5qbu]], [[5qbw]], [[5qbx]], [[5qbz]], [[5qc0]], [[5qc1]], [[5qc2]], [[5qc3]], [[5qc5]], [[5qc6]], [[5qc7]], [[5qc8]], [[5qc9]], [[5qca]], [[5qcb]] – hMCTSS (mutant) + piperidine inhibitor<br /> | **[[5qbu]], [[5qbw]], [[5qbx]], [[5qbz]], [[5qc0]], [[5qc1]], [[5qc2]], [[5qc3]], [[5qc5]], [[5qc6]], [[5qc7]], [[5qc8]], [[5qc9]], [[5qca]], [[5qcb]] – hMCTSS (mutant) + piperidine inhibitor<br /> | ||
**[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | **[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | ||
| - | **[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]] – hMCTSS+inhibitor<br /> | + | **[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]], [[6yyn]], [[6yyo]], [[6yyp]], [[6yyq]], [[6yyr]] – hMCTSS+inhibitor<br /> |
**[[2fye]], [[2g6d]] – hMCTSS (mutant)+inhibitor<br /> | **[[2fye]], [[2g6d]] – hMCTSS (mutant)+inhibitor<br /> | ||
**[[2fq9]], [[1ms6]] – hMCTSS +nitrile inhibitor<br /> | **[[2fq9]], [[1ms6]] – hMCTSS +nitrile inhibitor<br /> | ||
Current revision
3D Structures of Cathepsin
Updated on 15-November-2022
