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Chymotrypsin 3D structures

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(New page: == 3D Structures of Chymotrypsin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} The Chy precursor is the inactive '''chymotrypsinogen''' (Chygen) which ...)
Current revision (09:53, 23 November 2022) (edit) (undo)
 
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Line 27: Line 27:
**[[1acb]] – bChy+Elgin C <br />
**[[1acb]] – bChy+Elgin C <br />
**[[1cho]], [[1hja]] – bChyA+turkey ovomucoid third domain <br />
**[[1cho]], [[1hja]] – bChyA+turkey ovomucoid third domain <br />
 +
**[[7jrx]] – bChy + kunitz-type inhibitor<br />
* α-chymotrypsin + inhibitors
* α-chymotrypsin + inhibitors
-
**[[3bg4]] – ChyA chain A+guamerin <br />
+
**[[3bg4]] – bChyA chain A+guamerin <br />
**[[2p8o]] - bChyA chain A+benzohydroxamic acid/vanadate <br />
**[[2p8o]] - bChyA chain A+benzohydroxamic acid/vanadate <br />
-
**[[1eq9]] – Chy+PMSF – fire ant <br />
 
**[[2cha]] – bChyA+p-sulfinotoluene<br />
**[[2cha]] – bChyA+p-sulfinotoluene<br />
**[[6cha]] – bChyA+phenylethane boronic acid <br />
**[[6cha]] – bChyA+phenylethane boronic acid <br />
 +
**[[1eq9]] – Chy+PMSF – fire ant <br />
* γ-Chymotrypsin + inhibitors
* γ-Chymotrypsin + inhibitors
Line 51: Line 52:
* Native Chymotrypsinogen
* Native Chymotrypsinogen
-
**[[2cga]], [[1chg]], [[1ex3]] – bChygenA<br />
+
**[[2cga]], [[1chg]], [[1ex3]], [[7kty]], [[7ktz]], [[7ku0]], [[7ku1]], [[7ku2]], [[7ku3]] – bChygenA<br />
**[[2jet]] – rChygenB chain A,B <br />
**[[2jet]] – rChygenB chain A,B <br />
* Chymotrypsinogen + inhibitors
* Chymotrypsinogen + inhibitors
-
**[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – ''Locusta migratoria''<br />
 
**[[1k2i]] - bChygenA+7-hydroxycoumarin<br />
**[[1k2i]] - bChygenA+7-hydroxycoumarin<br />
**[[2y6t]] – bChygenA + ecotin<br />
**[[2y6t]] – bChygenA + ecotin<br />
Line 63: Line 63:
**[[3ru4]] - bChygenA + trypsin + Bowman-Birk inhibitor<br />
**[[3ru4]] - bChygenA + trypsin + Bowman-Birk inhibitor<br />
**[[1pyt]] – bChygenC + procarboxipeptidase + proproteinase<br />
**[[1pyt]] – bChygenC + procarboxipeptidase + proproteinase<br />
 +
**[[7qir]], [[7qis]], [[7qit]] - bChygenA + BPTI<br />
 +
**[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – locust<br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Chymotrypsin

Updated on 23-November-2022

The Chy precursor is the inactive chymotrypsinogen (Chygen) which gets cleaved 3 times by trypsin and chymotrypsin losing a 4 amino acid long peptide to become the active Chy. γ-Chy is a covalent acyl adduct of α-Chy. δ-Chy results when Chygen is cleaved only twice.

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Michal Harel

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