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ClpX

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<StructureSection load='1um8' size='350' side='right' caption='Helicobacter pylori ClpX complex with ADP (PDB entry [[1um8]])' scene='45/458468/Cv/1'>
<StructureSection load='1um8' size='350' side='right' caption='Helicobacter pylori ClpX complex with ADP (PDB entry [[1um8]])' scene='45/458468/Cv/1'>
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'''Clp'''X is a molecular chaperone which alters the shape of DNA during bacteriophage μ transposition.<ref>PMID:21736903</ref> For details see [[Molecular Playground/Hexameric ClpX]]
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'''Clp'''X or '''ATP-dependent Clp protease ATP-binding subunit ClpX''' is a molecular chaperone which alters the shape of DNA during bacteriophage μ transposition.<ref>PMID:21736903</ref> For details see [[Molecular Playground/Hexameric ClpX]]
<scene name='45/458468/Cv/4'>ADP binding site</scene> in ''Helicobacter pylori'' ClpX (PDB entry [[1um8]]).<ref>PMID:14514695</ref>
<scene name='45/458468/Cv/4'>ADP binding site</scene> in ''Helicobacter pylori'' ClpX (PDB entry [[1um8]]).<ref>PMID:14514695</ref>

Revision as of 10:33, 24 November 2022

Helicobacter pylori ClpX complex with ADP (PDB entry 1um8)

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3D structures of ClpX

Updated on 24-November-2022

6pba - MtClp N-terminal domain - Mycobacterium tuberculosis
3hte, 4i34, 4i5o, 4i63, 4i9k - EcClp - Escherichia coli
3hws, 4i4l - EcClp + ADP
4i81 - EcClp + ATPgS
6pp5 - EcClp + ADP – Cryo EM
6pp6, 6pp7, 6pp8 - EcClp + ADP + ATPgS – Cryo EM
6sfw - LmClp – Listeria monocytogenes - Cryo EM
6lsy - SpClp – Streptococcus pneumonia - Cryo EM
6lt4 - SpClp + ATPgS – Cryo EM

References

  1. ↑ Baker TA, Sauer RT. ClpXP, an ATP-powered unfolding and protein-degradation machine. Biochim Biophys Acta. 2012 Jan;1823(1):15-28. doi: 10.1016/j.bbamcr.2011.06.007. , Epub 2011 Jun 27. PMID:21736903 doi:http://dx.doi.org/10.1016/j.bbamcr.2011.06.007
  2. ↑ Kim DY, Kim KK. Crystal structure of ClpX molecular chaperone from Helicobacter pylori. J Biol Chem. 2003 Dec 12;278(50):50664-70. Epub 2003 Sep 26. PMID:14514695 doi:10.1074/jbc.M305882200

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Michal Harel, Alexander Berchansky

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