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8bbf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Structure of the IFT-A complex; IFT-A1 module== |
| - | + | <StructureSection load='8bbf' size='340' side='right'caption='[[8bbf]], [[Resolution|resolution]] 8.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8bbf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BBF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bbf OCA], [https://pdbe.org/8bbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bbf RCSB], [https://www.ebi.ac.uk/pdbsum/8bbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bbf ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/WDR19_HUMAN WDR19_HUMAN] Jeune syndrome;Senior-Loken syndrome;Juvenile nephronophthisis;Cranioectodermal dysplasia. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/WDR19_HUMAN WDR19_HUMAN] As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly (PubMed:20889716). Essential for functional IFT-A assembly and ciliary entry of GPCRs (PubMed:20889716). Associates with the BBSome complex to mediate ciliary transport (By similarity).[UniProtKB:Q3UGF1]<ref>PMID:20889716</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hesketh SJ]] | ||
| + | [[Category: Mukhopadhyay AG]] | ||
| + | [[Category: Nakamura D]] | ||
| + | [[Category: Roberts AJ]] | ||
| + | [[Category: Toropova K]] | ||
Current revision
Structure of the IFT-A complex; IFT-A1 module
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