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1bi3

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==STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR==
==STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR==
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<StructureSection load='1bi3' size='340' side='right' caption='[[1bi3]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='1bi3' size='340' side='right'caption='[[1bi3]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1bi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_diphtheriae"_kruse_in_flugge_1886 "bacillus diphtheriae" kruse in flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BI3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1bi3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BI3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bi3 OCA], [https://pdbe.org/1bi3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bi3 RCSB], [https://www.ebi.ac.uk/pdbsum/1bi3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bi3 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DTXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1717 "Bacillus diphtheriae" Kruse in Flugge 1886])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bi3 OCA], [http://pdbe.org/1bi3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bi3 RCSB], [http://www.ebi.ac.uk/pdbsum/1bi3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bi3 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI]] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
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[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bi3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bi3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1bi3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1bi3" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus diphtheriae kruse in flugge 1886]]
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[[Category: Corynebacterium diphtheriae]]
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[[Category: Hol, W G.J]]
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[[Category: Large Structures]]
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[[Category: Pohl, E]]
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[[Category: Hol WGJ]]
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[[Category: Dna-binding]]
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[[Category: Pohl E]]
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[[Category: Iron]]
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[[Category: Repressor]]
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[[Category: Transcription regulation]]
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Current revision

STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR

PDB ID 1bi3

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