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8bfh

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(New page: '''Unreleased structure''' The entry 8bfh is ON HOLD Authors: Basquin, J., Ozgur, S., Conti, E. Description: CNOT11 Category: Unreleased Structures Category: Conti, E [[Categor...)
Current revision (09:08, 28 December 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8bfh is ON HOLD
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==CNOT11==
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<StructureSection load='8bfh' size='340' side='right'caption='[[8bfh]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Basquin, J., Ozgur, S., Conti, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8bfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BFH FirstGlance]. <br>
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Description: CNOT11
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bfh OCA], [https://pdbe.org/8bfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bfh RCSB], [https://www.ebi.ac.uk/pdbsum/8bfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bfh ProSAT]</span></td></tr>
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[[Category: Conti, E]]
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</table>
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[[Category: Ozgur, S]]
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== Function ==
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[[Category: Basquin, J]]
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[https://www.uniprot.org/uniprot/CNO11_HUMAN CNO11_HUMAN] Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Basquin J]]
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[[Category: Conti E]]
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[[Category: Ozgur S]]

Current revision

CNOT11

PDB ID 8bfh

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