This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mqp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Mycobaterium tuberculosis transaminase BioA complexed with 2-hydrazinylbenzo[d]thiazole==
==Mycobaterium tuberculosis transaminase BioA complexed with 2-hydrazinylbenzo[d]thiazole==
-
<StructureSection load='4mqp' size='340' side='right' caption='[[4mqp]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
+
<StructureSection load='4mqp' size='340' side='right'caption='[[4mqp]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mqp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MQP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MQP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2B1:(4-{[(E)-1,3-BENZOTHIAZOL-2-YLDIAZENYL]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>2B1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2B1:(4-{[(E)-1,3-BENZOTHIAZOL-2-YLDIAZENYL]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>2B1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mqn|4mqn]], [[4mqo|4mqo]], [[4mqq|4mqq]], [[4mqr|4mqr]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqp OCA], [https://pdbe.org/4mqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mqp RCSB], [https://www.ebi.ac.uk/pdbsum/4mqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mqp ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioA, Rv1568, MT1619, MTCY336.35c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqp OCA], [http://pdbe.org/4mqp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mqp RCSB], [http://www.ebi.ac.uk/pdbsum/4mqp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mqp ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BIOA_MYCTU BIOA_MYCTU]] Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate.<ref>PMID:16984394</ref>
+
[https://www.uniprot.org/uniprot/BIOA_MYCTU BIOA_MYCTU] Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate.<ref>PMID:16984394</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 20:
==See Also==
==See Also==
-
*[[7%2C8-diaminopelargonic acid synthetase|7%2C8-diaminopelargonic acid synthetase]]
+
*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
 +
*[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
+
[[Category: Large Structures]]
-
[[Category: Dai, R]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Finzel, B C]]
+
[[Category: Dai R]]
-
[[Category: Plp]]
+
[[Category: Finzel BC]]
-
[[Category: Transaminase]]
+
-
[[Category: Transferase]]
+

Revision as of 10:01, 28 December 2022

Mycobaterium tuberculosis transaminase BioA complexed with 2-hydrazinylbenzo[d]thiazole

PDB ID 4mqp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mqp"
Personal tools