This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mrs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:03, 28 December 2022) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Structure of a bacterial Atm1-family ABC transporter==
==Structure of a bacterial Atm1-family ABC transporter==
-
<StructureSection load='4mrs' size='340' side='right' caption='[[4mrs]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
+
<StructureSection load='4mrs' size='340' side='right'caption='[[4mrs]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mrs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Novad Novad]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MRS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mrs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Novosphingobium_aromaticivorans_DSM_12444 Novosphingobium aromaticivorans DSM 12444]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MRS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDS:OXIDIZED+GLUTATHIONE+DISULFIDE'>GDS</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDS:OXIDIZED+GLUTATHIONE+DISULFIDE'>GDS</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mrs OCA], [https://pdbe.org/4mrs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mrs RCSB], [https://www.ebi.ac.uk/pdbsum/4mrs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mrs ProSAT]</span></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mrn|4mrn]], [[4mrp|4mrp]], [[4mrr|4mrr]], [[4mrv|4mrv]]</td></tr>
+
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATM1, Saro_2631 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=279238 NOVAD])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mrs OCA], [http://pdbe.org/4mrs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mrs RCSB], [http://www.ebi.ac.uk/pdbsum/4mrs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mrs ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ATM1_NOVAD ATM1_NOVAD] Mediates the ATP-dependent export of glutathione-conjugated substrates, such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions, such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons, such as dinitrobenzene.<ref>PMID:24604198</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Novad]]
+
[[Category: Large Structures]]
-
[[Category: Lee, J Y]]
+
[[Category: Novosphingobium aromaticivorans DSM 12444]]
-
[[Category: Lewinson, O]]
+
[[Category: Lee JY]]
-
[[Category: Rees, D C]]
+
[[Category: Lewinson O]]
-
[[Category: Yang, J G]]
+
[[Category: Rees DC]]
-
[[Category: Zhitnitsky, D]]
+
[[Category: Yang JG]]
-
[[Category: Exporter]]
+
[[Category: Zhitnitsky D]]
-
[[Category: Heavy metal resistance]]
+
-
[[Category: Membrane]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Transport protein]]
+

Current revision

Structure of a bacterial Atm1-family ABC transporter

PDB ID 4mrs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mrs"
Personal tools