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2k2s

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==structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii==
==structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii==
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<StructureSection load='2k2s' size='340' side='right' caption='[[2k2s]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
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<StructureSection load='2k2s' size='340' side='right'caption='[[2k2s]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K2S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2S FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k2t|2k2t]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2s OCA], [https://pdbe.org/2k2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2s RCSB], [https://www.ebi.ac.uk/pdbsum/2k2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2s ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MIC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii]), MIC6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k2s RCSB], [http://www.ebi.ac.uk/pdbsum/2k2s PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MIC1_TOXGO MIC1_TOXGO]] Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes.<ref>PMID:11447133</ref> <ref>PMID:11157983</ref> <ref>PMID:16166092</ref> <ref>PMID:17491595</ref> <ref>PMID:9027753</ref> [[http://www.uniprot.org/uniprot/MIC6_TOXGO MIC6_TOXGO]] Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme.<ref>PMID:11157983</ref> <ref>PMID:16166092</ref> <ref>PMID:18818666</ref>
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[https://www.uniprot.org/uniprot/MIC1_TOXGO MIC1_TOXGO] Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes.<ref>PMID:11447133</ref> <ref>PMID:11157983</ref> <ref>PMID:16166092</ref> <ref>PMID:17491595</ref> <ref>PMID:9027753</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2k2s" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: Matthews, S]]
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[[Category: Matthews S]]
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[[Category: Cell adhesion]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Egf-like domain]]
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[[Category: Lectin]]
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[[Category: Membrane]]
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[[Category: Microneme protein complex]]
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[[Category: Transmembrane]]
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[[Category: Virulence]]
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Current revision

structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii

PDB ID 2k2s

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