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2kgu
From Proteopedia
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==Spatial structure of purotoxin-1 in water== | ==Spatial structure of purotoxin-1 in water== | ||
| - | <StructureSection load='2kgu' size='340' side='right'caption='[[2kgu | + | <StructureSection load='2kgu' size='340' side='right'caption='[[2kgu]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kgu]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kgu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alopecosa_marikovskyi Alopecosa marikovskyi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KGU FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kgu OCA], [https://pdbe.org/2kgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kgu RCSB], [https://www.ebi.ac.uk/pdbsum/2kgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kgu ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TXPR1_ALOMR TXPR1_ALOMR] Inhibits P2RX3 receptors. Has an analgesic effect in rat. Enhances the high-affinity desensitization of P2RX3 receptors. At 50 nM, decreases the IC(50) for ambient ATP from 46.5 nM to 12.7 nM in mouse P2RX3.<ref>PMID:20437566</ref> <ref>PMID:22842000</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Alopecosa marikovskyi]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arseniev | + | [[Category: Arseniev A]] |
| - | [[Category: Grishin | + | [[Category: Grishin E]] |
| - | [[Category: Korolkova | + | [[Category: Korolkova Y]] |
| - | [[Category: Nadezhdin | + | [[Category: Nadezhdin K]] |
| - | [[Category: Pluzhnikov | + | [[Category: Pluzhnikov K]] |
| - | [[Category: Vassilevski | + | [[Category: Vassilevski A]] |
| - | + | ||
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Current revision
Spatial structure of purotoxin-1 in water
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