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4nac
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the N-terminal Domain of p15RS== | ==Crystal Structure of the N-terminal Domain of p15RS== | ||
| - | <StructureSection load='4nac' size='340' side='right' caption='[[4nac]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4nac' size='340' side='right'caption='[[4nac]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nac]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAC FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nac OCA], [https://pdbe.org/4nac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nac RCSB], [https://www.ebi.ac.uk/pdbsum/4nac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nac ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RPR1A_HUMAN RPR1A_HUMAN] Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.<ref>PMID:12470661</ref> <ref>PMID:22231121</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Jin | + | [[Category: Large Structures]] |
| - | [[Category: Mei | + | [[Category: Jin Z]] |
| - | [[Category: Ren | + | [[Category: Mei K]] |
| - | [[Category: Wang | + | [[Category: Ren F]] |
| - | + | [[Category: Wang Y]] | |
| - | + | ||
Revision as of 08:16, 11 January 2023
Crystal Structure of the N-terminal Domain of p15RS
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Categories: Homo sapiens | Large Structures | Jin Z | Mei K | Ren F | Wang Y
