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4nd3

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<StructureSection load='4nd3' size='340' side='right'caption='[[4nd3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4nd3' size='340' side='right'caption='[[4nd3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nd3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ND3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nd3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ND3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nd1|4nd1]], [[4nd2|4nd2]], [[4nd4|4nd4]], [[4nd5|4nd5]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nd3 OCA], [https://pdbe.org/4nd3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nd3 RCSB], [https://www.ebi.ac.uk/pdbsum/4nd3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nd3 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd7_480, LDH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nd3 OCA], [http://pdbe.org/4nd3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nd3 RCSB], [http://www.ebi.ac.uk/pdbsum/4nd3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nd3 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5CYZ2_CRYPI Q5CYZ2_CRYPI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Crypi]]
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[[Category: Cryptosporidium parvum Iowa II]]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chattopadhyay, D]]
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[[Category: Chattopadhyay D]]
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[[Category: Cook, W J]]
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[[Category: Cook WJ]]
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[[Category: Nad binding]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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Revision as of 08:22, 11 January 2023

Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide)

PDB ID 4nd3

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