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4nlh

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<StructureSection load='4nlh' size='340' side='right'caption='[[4nlh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4nlh' size='340' side='right'caption='[[4nlh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NLH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NLH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN TAX1BP1, PRO0105, T6BP, TAX1BP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nlh OCA], [https://pdbe.org/4nlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nlh RCSB], [https://www.ebi.ac.uk/pdbsum/4nlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nlh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nlh OCA], [http://pdbe.org/4nlh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nlh RCSB], [http://www.ebi.ac.uk/pdbsum/4nlh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nlh ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TAXB1_HUMAN TAXB1_HUMAN]] Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.<ref>PMID:10435631</ref> <ref>PMID:10920205</ref>
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[https://www.uniprot.org/uniprot/TAXB1_HUMAN TAXB1_HUMAN] Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.<ref>PMID:10435631</ref> <ref>PMID:10920205</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Du, Z]]
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[[Category: Du Z]]
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[[Category: Huang, X]]
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[[Category: Huang X]]
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[[Category: Wang, G]]
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[[Category: Wang G]]
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[[Category: Yang, Y]]
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[[Category: Yang Y]]
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[[Category: Zhu, J]]
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[[Category: Zhu J]]
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[[Category: Ig like fold]]
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[[Category: Protein binding]]
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Revision as of 08:33, 11 January 2023

SKICH domain of human TAX1BP1

PDB ID 4nlh

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OCA

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