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4nnr

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Current revision (08:36, 11 January 2023) (edit) (undo)
 
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<StructureSection load='4nnr' size='340' side='right'caption='[[4nnr]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='4nnr' size='340' side='right'caption='[[4nnr]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nnr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nnr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FK5:8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'>FK5</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FK5:8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'>FK5</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FKBP2, FKBP13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnr OCA], [https://pdbe.org/4nnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnr RCSB], [https://www.ebi.ac.uk/pdbsum/4nnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnr ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnr OCA], [http://pdbe.org/4nnr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnr RCSB], [http://www.ebi.ac.uk/pdbsum/4nnr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FKBP2_HUMAN FKBP2_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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[https://www.uniprot.org/uniprot/FKBP2_HUMAN FKBP2_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
==See Also==
==See Also==
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*[[FK506 binding protein|FK506 binding protein]]
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*[[FKBP 3D structures|FKBP 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Clardy J]]
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[[Category: Clardy, J]]
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[[Category: Liang J]]
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[[Category: Liang, J]]
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[[Category: Martin PK]]
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[[Category: Martin, P K]]
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[[Category: Schreiber SL]]
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[[Category: Schreiber, S L]]
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[[Category: Schultz LW]]
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[[Category: Schultz, L W]]
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[[Category: Fkbp]]
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[[Category: Immunophilin]]
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[[Category: Isomerase]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Loop crossing]]
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[[Category: Peptidyl-prolyl isomerase]]
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Current revision

FKBP13-FK506 Complex

PDB ID 4nnr

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