This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8dwu
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==SPOP W22R Form 1== | |
| - | + | <StructureSection load='8dwu' size='340' side='right'caption='[[8dwu]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8dwu]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DWU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dwu OCA], [https://pdbe.org/8dwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dwu RCSB], [https://www.ebi.ac.uk/pdbsum/8dwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dwu ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Cuneo | + | == Function == |
| - | [[Category: Mittag | + | [https://www.uniprot.org/uniprot/SPOP_HUMAN SPOP_HUMAN] Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.<ref>PMID:14528312</ref> <ref>PMID:15897469</ref> <ref>PMID:16524876</ref> |
| - | [[Category: O | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cuneo MJ]] | ||
| + | [[Category: Mittag T]] | ||
| + | [[Category: O'Flynn B]] | ||
Current revision
SPOP W22R Form 1
| |||||||||||
