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4ntw
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==Structure of acid-sensing ion channel in complex with snake toxin== | ==Structure of acid-sensing ion channel in complex with snake toxin== | ||
| - | <StructureSection load='4ntw' size='340' side='right' caption='[[4ntw]], [[Resolution|resolution]] 2.07Å' scene=''> | + | <StructureSection load='4ntw' size='340' side='right'caption='[[4ntw]], [[Resolution|resolution]] 2.07Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ntw]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ntw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Micrurus_tener_tener Micrurus tener tener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NTW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ntw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntw OCA], [https://pdbe.org/4ntw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ntw RCSB], [https://www.ebi.ac.uk/pdbsum/4ntw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntw ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ASIC1_CHICK ASIC1_CHICK] Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride (By similarity).<ref>PMID:16002453</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Ion channels|Ion channels]] | + | *[[Ion channels 3D structures|Ion channels 3D structures]] |
| + | *[[Phospholipase A2 homolog|Phospholipase A2 homolog]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Gallus gallus]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Baconguis | + | [[Category: Micrurus tener tener]] |
| - | [[Category: Bohlen | + | [[Category: Baconguis I]] |
| - | [[Category: Goehring | + | [[Category: Bohlen CJ]] |
| - | [[Category: Gouaux | + | [[Category: Goehring A]] |
| - | [[Category: Julius | + | [[Category: Gouaux E]] |
| - | + | [[Category: Julius D]] | |
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Current revision
Structure of acid-sensing ion channel in complex with snake toxin
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