4o4l
From Proteopedia
(Difference between revisions)
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<StructureSection load='4o4l' size='340' side='right'caption='[[4o4l]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4o4l' size='340' side='right'caption='[[4o4l]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4o4l]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4o4l]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O4L FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EP:EPOTHILONE+A'>EP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POU:PELORUSIDE+A'>POU</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EP:EPOTHILONE+A'>EP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POU:PELORUSIDE+A'>POU</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o4l OCA], [https://pdbe.org/4o4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o4l RCSB], [https://www.ebi.ac.uk/pdbsum/4o4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o4l ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
- | *[[Stathmin|Stathmin]] | + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] |
- | *[[Tubulin|Tubulin]] | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] |
*[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]] | *[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]] | ||
- | *[[User:Alisa Cario|User:Alisa Cario]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
- | [[Category: | + | [[Category: Gallus gallus]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Altmann | + | [[Category: Rattus norvegicus]] |
- | [[Category: Bargsten | + | [[Category: Altmann KH]] |
- | [[Category: Diaz | + | [[Category: Bargsten K]] |
- | [[Category: Marsh | + | [[Category: Diaz JF]] |
- | [[Category: Miller | + | [[Category: Marsh M]] |
- | [[Category: Northcote | + | [[Category: Miller JH]] |
- | [[Category: Prota | + | [[Category: Northcote PT]] |
- | [[Category: Steinmetz | + | [[Category: Prota AE]] |
- | + | [[Category: Steinmetz MO]] | |
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Revision as of 08:55, 18 January 2023
Tubulin-Peloruside A-Epothilone A complex
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