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1vlu

From Proteopedia

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[[Image:1vlu.gif|left|200px]]
 
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{{Structure
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==Crystal structure of Gamma-glutamyl phosphate reductase (yor323c) from Saccharomyces cerevisiae at 2.40 A resolution==
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|PDB= 1vlu |SIZE=350|CAPTION= <scene name='initialview01'>1vlu</scene>, resolution 2.29&Aring;
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<StructureSection load='1vlu' size='340' side='right'caption='[[1vlu]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1vlu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VLU FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-5-semialdehyde_dehydrogenase Glutamate-5-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.41 1.2.1.41] </span>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|GENE= PRO2, YOR323C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vlu OCA], [https://pdbe.org/1vlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vlu RCSB], [https://www.ebi.ac.uk/pdbsum/1vlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vlu ProSAT], [https://www.topsan.org/Proteins/JCSG/1vlu TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0014 ProA]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vlu OCA], [http://www.ebi.ac.uk/pdbsum/1vlu PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1vlu RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PROA_YEAST PROA_YEAST] Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
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== Evolutionary Conservation ==
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'''Crystal structure of Gamma-glutamyl phosphate reductase (yor323c) from Saccharomyces cerevisiae at 2.40 A resolution'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vl/1vlu_consurf.spt"</scriptWhenChecked>
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1VLU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLU OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Glutamate-5-semialdehyde dehydrogenase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vlu ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
 
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: gamma-glutamyl phosphate reductase]]
 
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[[Category: jcsg]]
 
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[[Category: joint center for structural genomic]]
 
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[[Category: protein structure initiative]]
 
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[[Category: psi]]
 
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[[Category: structural genomic]]
 
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[[Category: yor323c]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:27:05 2008''
 

Current revision

Crystal structure of Gamma-glutamyl phosphate reductase (yor323c) from Saccharomyces cerevisiae at 2.40 A resolution

PDB ID 1vlu

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