1vq1

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<StructureSection load='1vq1' size='340' side='right'caption='[[1vq1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1vq1' size='340' side='right'caption='[[1vq1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vq1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1VQ1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vq1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VQ1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vq1 OCA], [https://pdbe.org/1vq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vq1 RCSB], [https://www.ebi.ac.uk/pdbsum/1vq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vq1 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vq1 TOPSAN]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM0488 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1vq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vq1 OCA], [http://pdbe.org/1vq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vq1 RCSB], [http://www.ebi.ac.uk/pdbsum/1vq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vq1 ProSAT], [http://www.topsan.org/Proteins/JCSG/1vq1 TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRMC_THEMA PRMC_THEMA]] Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
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[https://www.uniprot.org/uniprot/PRMC_THEMA PRMC_THEMA] Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thema]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Structural genomic]]
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[[Category: Jcsg]]
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[[Category: N5-glutamine methyltransferase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Tm0488]]
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[[Category: Transferase]]
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Revision as of 06:42, 25 January 2023

Crystal structure of N5-glutamine methyltransferase, HemK(EC 2.1.1.-) (TM0488) from Thermotoga maritima at 2.80 A resolution

PDB ID 1vq1

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