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1vr0

From Proteopedia

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[[Image:1vr0.gif|left|200px]]
 
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{{Structure
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==Crystal structure of putative 2-phosphosulfolactate phosphatase (15026306) from Clostridium acetobutylicum at 2.6 A resolution==
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|PDB= 1vr0 |SIZE=350|CAPTION= <scene name='initialview01'>1vr0</scene>, resolution 2.49&Aring;
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<StructureSection load='1vr0' size='340' side='right'caption='[[1vr0]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=3SL:(2R)-3-SULFOLACTIC+ACID'>3SL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1vr0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VR0 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-phosphosulfolactate_phosphatase 2-phosphosulfolactate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.71 3.1.3.71] </span>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3SL:(2R)-3-SULFOLACTIC+ACID'>3SL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|GENE= comB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 Clostridium acetobutylicum])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr0 OCA], [https://pdbe.org/1vr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vr0 RCSB], [https://www.ebi.ac.uk/pdbsum/1vr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr0 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vr0 TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00886 PRK00886]</span>
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr0 OCA], [http://www.ebi.ac.uk/pdbsum/1vr0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vr0 RCSB]</span>
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[https://www.uniprot.org/uniprot/COMB_CLOAB COMB_CLOAB]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Crystal structure of putative 2-phosphosulfolactate phosphatase (15026306) from Clostridium acetobutylicum at 2.6 A resolution'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/1vr0_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1VR0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR0 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vr0 ConSurf].
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Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site., DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Agarwalla S, Brittain SM, Miller MD, Abdubek P, Ambing E, Axelrod HL, Canaves JM, Chiu HJ, Deacon AM, Duan L, Elsliger MA, Godzik A, Grzechnik SK, Hale J, Hampton E, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Kreusch A, Kuhn P, Lesley SA, Levin I, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Quijano K, Reyes R, Rife CL, Spraggon G, Stevens RC, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA, Proteins. 2006 Nov 15;65(3):771-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16927339 16927339]
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<div style="clear:both"></div>
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[[Category: 2-phosphosulfolactate phosphatase]]
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__TOC__
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</StructureSection>
[[Category: Clostridium acetobutylicum]]
[[Category: Clostridium acetobutylicum]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: 15026306]]
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[[Category: jcsg]]
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[[Category: joint center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: putative 2-phosphosulfolactate phosphatase]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:27:34 2008''
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Current revision

Crystal structure of putative 2-phosphosulfolactate phosphatase (15026306) from Clostridium acetobutylicum at 2.6 A resolution

PDB ID 1vr0

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