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2g8l

From Proteopedia

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{{Seed}}
 
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[[Image:2g8l.png|left|200px]]
 
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==Crystal structure of a duf89 family protein (ph1575) from pyrococcus horikoshii at 2.04 A resolution==
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The line below this paragraph, containing "STRUCTURE_2g8l", creates the "Structure Box" on the page.
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<StructureSection load='2g8l' size='340' side='right'caption='[[2g8l]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g8l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G8L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g8l OCA], [https://pdbe.org/2g8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g8l RCSB], [https://www.ebi.ac.uk/pdbsum/2g8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g8l ProSAT], [https://www.topsan.org/Proteins/JCSG/2g8l TOPSAN]</span></td></tr>
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{{STRUCTURE_2g8l| PDB=2g8l | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of a protein of unknown function from DUF180 family (3258004) from Pyrococcus horikoshii at 2.04 A resolution.===
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[https://www.uniprot.org/uniprot/D89S1_PYRHO D89S1_PYRHO] Metal-dependent phosphatase with probable damage-control functions (PubMed:27322068). Shows phosphatase activity against p-nitrophenyl phosphate (pNPP), but natural substrates have not been identified yet (PubMed:27322068). Low phosphatase activity against 8-oxo nucleotides suggests that it could hydrolyze oxidatively damaged purine nucleotides or their biosynthetic intermediates (PubMed:27322068).<ref>PMID:27322068</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2G8L is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8L OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/2g8l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g8l ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: 3258004]]
 
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[[Category: Hypothetical protein]]
 
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[[Category: Jcsg]]
 
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[[Category: Joint center for structural genomic]]
 
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[[Category: Protein structure initiative]]
 
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[[Category: Psi]]
 
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[[Category: Structural genomic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:51:59 2008''
 

Current revision

Crystal structure of a duf89 family protein (ph1575) from pyrococcus horikoshii at 2.04 A resolution

PDB ID 2g8l

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