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2hxv

From Proteopedia

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(New page: 200px<br /><applet load="2hxv" size="350" color="white" frame="true" align="right" spinBox="true" caption="2hxv, resolution 1.800&Aring;" /> '''Crystal structure o...)
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[[Image:2hxv.gif|left|200px]]<br /><applet load="2hxv" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2hxv, resolution 1.800&Aring;" />
 
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'''Crystal structure of Diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (TM1828) from Thermotoga maritima at 1.80 A resolution'''<br />
 
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==About this Structure==
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==Crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828) from thermotoga maritima at 1.80 A resolution==
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2HXV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXV OCA].
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<StructureSection load='2hxv' size='340' side='right'caption='[[2hxv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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[[Category: Single protein]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hxv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HXV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxv OCA], [https://pdbe.org/2hxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hxv RCSB], [https://www.ebi.ac.uk/pdbsum/2hxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hxv ProSAT], [https://www.topsan.org/Proteins/JCSG/2hxv TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X2E8_THEMA Q9X2E8_THEMA] Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.[PIRNR:PIRNR006769]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hxv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hxv ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
 
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[[Category: CL]]
 
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[[Category: GOL]]
 
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[[Category: NDP]]
 
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[[Category: ZN]]
 
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[[Category: diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase]]
 
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[[Category: jcsg]]
 
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[[Category: joint center for structural genomics]]
 
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[[Category: protein structure initiative]]
 
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[[Category: psi-2]]
 
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[[Category: structural genomics]]
 
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[[Category: tm1828]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 20:31:02 2008''
 

Current revision

Crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828) from thermotoga maritima at 1.80 A resolution

PDB ID 2hxv

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