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2r3b

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[[Image:2r3b.jpg|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF a ribokinase-like superfamily protein (EF1790) FROM ENTEROCOCCUS FAECALIS V583 AT 1.80 A RESOLUTION==
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|PDB= 2r3b |SIZE=350|CAPTION= <scene name='initialview01'>2r3b</scene>, resolution 1.800&Aring;
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<StructureSection load='2r3b' size='340' side='right'caption='[[2r3b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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<table><tr><td colspan='2'>[[2r3b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R3B FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|GENE= NP_815490.1, EF_1790 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226185 Enterococcus faecalis V583])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r3b OCA], [https://pdbe.org/2r3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r3b RCSB], [https://www.ebi.ac.uk/pdbsum/2r3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r3b ProSAT], [https://www.topsan.org/Proteins/JCSG/2r3b TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal structure of a putative kinase in the ribokinase-like superfamily from Enterococcus faecalis V583 (NP_815490.1) at 1.80 A resolution'''
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[https://www.uniprot.org/uniprot/NNRD_ENTFA NNRD_ENTFA] Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[HAMAP-Rule:MF_01965]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2R3B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3B OCA].
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<jmolCheckbox>
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[[Category: Enterococcus faecalis v583]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r3/2r3b_consurf.spt"</scriptWhenChecked>
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[[Category: Single protein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: CL]]
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</jmolCheckbox>
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[[Category: EDO]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r3b ConSurf].
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[[Category: MG]]
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<div style="clear:both"></div>
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[[Category: jcsg]]
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__TOC__
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[[Category: joint center for structural genomic]]
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</StructureSection>
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[[Category: np_815490 1]]
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[[Category: Enterococcus faecalis V583]]
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[[Category: protein structure initiative]]
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[[Category: Large Structures]]
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[[Category: psi-2]]
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[[Category: putative kinase in the ribokinase-like superfamily from enterococcus faecalis v583]]
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[[Category: structural genomic]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:32:12 2008''
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Current revision

CRYSTAL STRUCTURE OF a ribokinase-like superfamily protein (EF1790) FROM ENTEROCOCCUS FAECALIS V583 AT 1.80 A RESOLUTION

PDB ID 2r3b

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