This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3b5q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:51, 25 January 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3b5q.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of a putative sulfatase (NP_810509.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.40 A resolution==
-
The line below this paragraph, containing "STRUCTURE_3b5q", creates the "Structure Box" on the page.
+
<StructureSection load='3b5q' size='340' side='right'caption='[[3b5q]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3b5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B5Q FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b5q OCA], [https://pdbe.org/3b5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b5q RCSB], [https://www.ebi.ac.uk/pdbsum/3b5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b5q ProSAT], [https://www.topsan.org/Proteins/JCSG/3b5q TOPSAN]</span></td></tr>
-
{{STRUCTURE_3b5q| PDB=3b5q | SCENE= }}
+
</table>
-
 
+
== Function ==
-
'''Crystal structure of a putative sulfatase (NP_810509.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.40 A resolution'''
+
[https://www.uniprot.org/uniprot/HEXSF_BACTN HEXSF_BACTN] Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS). 2-O-sulfatase active on unsaturated non-reducing end hexuronate units. Has a slight preference for HS-derived structures (PubMed:25002587). GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).<ref>PMID:25002587</ref> <ref>PMID:25002587</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
3B5Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5Q OCA].
+
<jmolCheckbox>
-
[[Category: Bacteria]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/3b5q_consurf.spt"</scriptWhenChecked>
-
[[Category: Single protein]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: JCSG, Joint Center for Structural Genomics.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Hydrolase]]
+
</jmolCheckbox>
-
[[Category: Jcsg]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b5q ConSurf].
-
[[Category: Joint center for structural genomic]]
+
<div style="clear:both"></div>
-
[[Category: Np_810509 1]]
+
== References ==
-
[[Category: Protein structure initiative]]
+
<references/>
-
[[Category: Psi-2]]
+
__TOC__
-
[[Category: Putative sulfatase]]
+
</StructureSection>
-
[[Category: Structural genomic]]
+
[[Category: Bacteroides thetaiotaomicron VPI-5482]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:25:11 2008''
+
[[Category: Large Structures]]

Current revision

Crystal structure of a putative sulfatase (NP_810509.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.40 A resolution

PDB ID 3b5q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3b5q"
Personal tools