This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jyo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:07, 25 January 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Structure of the Salmonella Virulence Effector SptP in Complex with its Secretion Chaperone SicP==
==Structure of the Salmonella Virulence Effector SptP in Complex with its Secretion Chaperone SicP==
-
<StructureSection load='1jyo' size='340' side='right' caption='[[1jyo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+
<StructureSection load='1jyo' size='340' side='right'caption='[[1jyo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1jyo]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JYO FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1jyo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYO FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jyo OCA], [http://pdbe.org/1jyo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jyo RCSB], [http://www.ebi.ac.uk/pdbsum/1jyo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jyo ProSAT]</span></td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jyo OCA], [https://pdbe.org/1jyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jyo RCSB], [https://www.ebi.ac.uk/pdbsum/1jyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jyo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/SICP_SALTY SICP_SALTY]] Molecular chaperone required for sptP stabilization and secretion. [[http://www.uniprot.org/uniprot/SPTP_SALTY SPTP_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear.<ref>PMID:8866485</ref> <ref>PMID:10499590</ref> <ref>PMID:11163217</ref>
+
[https://www.uniprot.org/uniprot/SICP_SALTY SICP_SALTY] Molecular chaperone required for sptP stabilization and secretion.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 17:
</div>
</div>
<div class="pdbe-citations 1jyo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1jyo" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Galan, J E]]
+
[[Category: Large Structures]]
-
[[Category: Stebbins, C E]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-
[[Category: Bacterial pathogenesis]]
+
[[Category: Galan JE]]
-
[[Category: Chaperone]]
+
[[Category: Stebbins CE]]
-
[[Category: Infectious disease]]
+
-
[[Category: Protein folding]]
+
-
[[Category: Salmonella]]
+
-
[[Category: Sicp]]
+
-
[[Category: Sptp]]
+
-
[[Category: Type iii secretion]]
+
-
[[Category: Unfolded]]
+
-
[[Category: Virulence factor]]
+

Current revision

Structure of the Salmonella Virulence Effector SptP in Complex with its Secretion Chaperone SicP

PDB ID 1jyo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jyo"
Personal tools