DNA damage-binding protein
From Proteopedia
(Difference between revisions)
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**[[6dsz]] – hDDB + DET1 peptide<br /> | **[[6dsz]] – hDDB + DET1 peptide<br /> | ||
**[[4a11]], [[6fcv]] – hDDB + DNA excision repair protein ERCC-8<br /> | **[[4a11]], [[6fcv]] – hDDB + DNA excision repair protein ERCC-8<br /> | ||
| + | **[[8d7x]], [[8d7y]] – hDDB + cereblon <br /> | ||
| + | **[[8cvp]] – hDDB + cereblon – Cryo EM<br /> | ||
| + | **[[6zue]] – hDDB + DCAF1<br /> | ||
| + | **[[8ajn]] – hDDB + DCAF1 – Cryo EM<br /> | ||
| + | **[[7ukn]] – hDDB + herpes virus protein br /> | ||
| + | **[[7p7b]] – hDDB + VPRBP – Cryo EM<br /> | ||
*DDB1 ternary complex | *DDB1 ternary complex | ||
| - | **[[4ci1]], [[4ci2]], [[4ci3]], [[4tz4]] – hDDB + cereblon + thalidomide derivative<br /> | + | **[[4ci1]], [[4ci2]], [[4ci3]], [[4tz4]], [[8d81]] – hDDB + cereblon + thalidomide derivative<br /> |
**[[5v3o]] – hDDB + cereblon + piperidine derivative<br /> | **[[5v3o]] – hDDB + cereblon + piperidine derivative<br /> | ||
**[[5fqd]] – hDDB + cereblon + casein kinase 1<br /> | **[[5fqd]] – hDDB + cereblon + casein kinase 1<br /> | ||
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**[[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] – hDDB + cereblon + BRD4<br /> | **[[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] – hDDB + cereblon + BRD4<br /> | ||
**[[7lps]] – hDDB + cereblon + IKAROS<br /> | **[[7lps]] – hDDB + cereblon + IKAROS<br /> | ||
| + | **[[8d7u]], [[8d7v]], [[8d7w]] – hDDB + cereblon + mezigdomide<br /> | ||
**[[6h0f]] – hDDB (mutant) + cereblon + IKAROS<br /> | **[[6h0f]] – hDDB (mutant) + cereblon + IKAROS<br /> | ||
**[[6h0g]] – hDDB (mutant) + cereblon + ZNF692<br /> | **[[6h0g]] – hDDB (mutant) + cereblon + ZNF692<br /> | ||
**[[6td3]] – hDDB + cyclin-dependent kinase 12 + cyclin-K<br /> | **[[6td3]] – hDDB + cyclin-dependent kinase 12 + cyclin-K<br /> | ||
| + | **[[7zn7]], [[7znn]] – hDDB (mutant) + herpes virus protein + STAT2 – Cryo EM<br /> | ||
| + | **[[6zx9]] – hDDB + SIV protein + VPRBP <br /> | ||
| + | **[[8ajm]], [[8ajo]] – hDDB + DCAF1 + CCT5 – Cryo EM<br /> | ||
*DDB1 quaternary complex | *DDB1 quaternary complex | ||
**[[6uml]] – hDDB + cereblon + ZNF797 + thalidomide derivative <br /> | **[[6uml]] – hDDB + cereblon + ZNF797 + thalidomide derivative <br /> | ||
| + | **[[6bn7]] – hDDB + cereblon + BRD4 + piperidine derivative<br /> | ||
| + | **[[8d7z]], [[8d80]] – hDDB + cereblon + IKAROS + drug<br /> | ||
**[[2hye]] – hDDB + simian virus 5 protein + cullin-4A + ring-box protein 1<br /> | **[[2hye]] – hDDB + simian virus 5 protein + cullin-4A + ring-box protein 1<br /> | ||
| + | **[[5jk7]] – hDDB + HIV protein + uracil-DNA glycosylase + VPRBP <br /> | ||
| + | **[[7v7c]] – hDDB + HIV protein + uracil-DNA glycosylase + VPRBP – Cryo EM<br /> | ||
| + | **[[7okq]] – hDDB + DCAF1 + cullin-4A + RBX1 – Cryo EM<br /> | ||
**[[6pai]], [[6q0r]], [[6ue5]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + sulfonamide derivative<br /> | **[[6pai]], [[6q0r]], [[6ue5]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + sulfonamide derivative<br /> | ||
**[[6q0v]], [[6q0w]], [[6ud7]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + anti-cancer drug<br /> | **[[6q0v]], [[6q0w]], [[6ud7]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + anti-cancer drug<br /> | ||
**[[6sj7]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + anti-cancer drug – Cryo EM<br /> | **[[6sj7]] – hDDB + DDA1 + RNA-binding protein 39 + DET1 + anti-cancer drug – Cryo EM<br /> | ||
| - | **[[ | + | **[[7oo3]], [[7oob]], [[7oop]], [[7opc]], [[7opd]] – hDDB in transcription-DNA repair coupling – Cryo EM<br /> |
| + | |||
*DDB1+DDB2 | *DDB1+DDB2 | ||
Revision as of 10:49, 30 January 2023
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3D Structures of DNA damage-binding protein
Updated on 30-January-2023
References
- ↑ Guerrero-Santoro J, Kapetanaki MG, Hsieh CL, Gorbachinsky I, Levine AS, Rapic-Otrin V. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A. Cancer Res. 2008 Jul 1;68(13):5014-22. PMID:18593899 doi:68/13/5014
