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7vsf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==crystal structure of BRD2-BD1 in complex with purine derivative== | |
| - | + | <StructureSection load='7vsf' size='340' side='right'caption='[[7vsf]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7vsf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VSF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7UM:3-methyl-7-propyl-purine-2,6-dione'>7UM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vsf OCA], [https://pdbe.org/7vsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vsf RCSB], [https://www.ebi.ac.uk/pdbsum/7vsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vsf ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Ashok | + | [https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> |
| - | [[Category: Deshmukh | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arole A]] | ||
| + | [[Category: Ashok S]] | ||
| + | [[Category: Deshmukh P]] | ||
| + | [[Category: Mathur S]] | ||
| + | [[Category: Padmanabhan B]] | ||
Revision as of 11:16, 1 February 2023
crystal structure of BRD2-BD1 in complex with purine derivative
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